急性重症胰腺炎并发ARDS多因素回归分析

Multivariate regression analysis for severe acute pancreatitis patients with ARDS

目的:探讨急性重症胰腺炎并发ARDS的危险因素,为其临床防治提供可参考依据。方法:回顾分析243例急性重症胰腺炎患者的临床资料,对发生ARDS患者应用多因素回归分析进行多因素分析。结果:243例急性重症胰腺炎患者中有54例发生ARDS,发生率为22.22%,单因素分析结果显示性别、低蛋白血症与急性重症胰腺炎并发ARDS密切相关(P<0.05),多因素分析结果显示女性(P=0.009)、低蛋白血症(P=0.000)、高甘油三酯(P=0.010)是急性重症胰腺炎发生ARDS的独立危险因素。结论:急性重症胰腺炎患者发生ARDS与性别、低蛋白血症、高甘油三酯存在密切的相关性,对有上述因素的患者进行早期防治有重要的临床意义。

Objective：To discuss the risk factors for severe acute pancreatitis patients with ARDS so as to guide the clinical prevention and treatment.Method：A total of 243 patients with severe acute pancreatitis were retrospectively analyzed,then the multivariate regression analysis was performed to those with ARDS.Result：Of 243 patients with severe acute pancreatitis,54（22.22%）developed ARDS.The result of univariate analysis indicated that the factors such as sex,hypoalbuminemia influenced the ARDS development in the severe acute pancreatitis（P0.05）;The result of multivariate analysis showed that the female（P=0.009）,hypoalbuminemia（P=0.000）,hypertriglyceridemia（P=0.010）were the independent risk factors that influenced the ARDS development in the severe acute pancreatitis.Conclusion：The incidence of ARDS in the severe acute pancreatitis is related to the sex,hypoalbuminemia,and hypertriglyceridemia;it is of great significance to implement necessary interventions for the risk factors.