组织多普勒Tei指数评价肥胖性心肌病左、右心功能的价值

Value of Tei index measured by tissue Doppler imaging in assessing ventricular function of patients with obesity

目的探讨组织多普勒技术测量Tei指数评价肥胖患者心功能的价值。方法 148例体格检查者根据体质指数(BMI)分为对照组50例、超重组50例、肥胖组48例,均行常规超声心动图和组织多普勒检查,计算出同步Tei指数,比较各组心脏结构和功能指标,并对左、右心Tei指数进行相关分析。结果超重组左心室Tei指数较对照组高(P<0.05),右心室Tei指数与对照组比较差异无统计学意义(P>0.05);肥胖组左心室Tei指数明显高于对照组及超重组(P<0.01),右心室Tei指数高于对照组(P<0.05),与超重组比较差异无统计学意义(P>0.05);所有受试者的右心室Tei指数与左心室Tei指数呈正相关(r=0.645,P<0.01)。结论超重者可出现左心功能减低,肥胖者左、右心功能均减低。组织多普勒联合Tei指数可以敏感、全面地综合评价心室整体功能表现,为临床定量评价心功能提供一种新的手段。

Objective To explore the value of Tei index measured by tissue Doppler imaging （TDI） in assess-ing ventricular function of patients with obesity. Methods A total of 148 persons underwent medical examination were divided into control group （50 subjects）, overweight group （50 subjects） and obesity group （48 subjects） by body mass index （BMI）. All subjects underwent routine echocardiography and TDI, and Tei index was calculated . The pa-rameters of heart structure and ventricular function of each group were comparatively analyzed. The correlative analy-sis of the Tei index of the left ventricular （LV） and the right ventricular （RV） was made in all subjects. Results LV Tei index in the overweight group was significantly higher than that in the control group （P〈0.05）, but there was no statistically significant difference in the RV Tei index between the two groups （P〉0.05）. LV Tei index in the obesity group was significantly higher than those in the control group and overweight group （P〈0.01）. RV Tei index in the obe-sity group was significantly higher than that in the control group （P〈0.05）, but was not statistically significantly differ-ent from that in the overweight group （P〉0.05）. There was a positive correlation between LV and RV＇s Tei index （P〈0.01）. Conclusion Overweight could lead to decline of LV function, and obesity could lead to decline of LV and RV functions. Tei index measured by TDI could predict ventricular function roundly and sensitively, which provided a promising modality for quantitative estimation of ventricular function.