期刊文献+

左西孟旦在顽固性心力衰竭中的临床应用 被引量:2

Clinical application of levosimendan in refractory heart failure
下载PDF
导出
摘要 目的探索顽固性心力衰竭患者采用左西孟旦治疗的临床效果。方法顽固性心力衰竭患者34例,按用药方式的不同分为治疗组和对照组,每组17例。对照组患者给予常规治疗,治疗组患者在对照组的基础上加用左西孟旦治疗,观察两组患者的临床效果和不良反应情况。结果治疗组患者的血压和呼吸困难程度评分情况显著优于对照组,治疗组患者的临床射血分数和钾离子情况显著优于对照组,差异有统计学意义(P<0.05)。结论顽固性心力衰竭患者加用左西孟旦治疗,有效的改善了患者的临床症状,明确了用药后产生的不良反应为室性过早博动和低血钾。 Objective To explore the clinical effect of levosimendan in the treatment ot patmnts with refractory heart failure. Methods A total of 34 cases meeting the standard in our hospital were divided into treatment group and control group according to different drug use, and each group contained 17 cases. The control group was given conventional treatment, and the treatment group received levosimendan in addition. The clinical effect and ad~/erse reactions were observed. Results The scores of blood pressure and degree of dyspnea were all better than the control group. The clinical ejection fraction and potassium ion of the observation group were better than the control group. The differences had statistical significance (P〈0.05). Conclusion Levosimendan treatment for patients with refractory heart failure can effectively improve the clinical symptoms, and its adverse reactions after treatment are ventricular premature beats and hypokalemia.
作者 王赛
出处 《中国实用医药》 2014年第25期32-33,共2页 China Practical Medicine
关键词 左西孟旦 顽固性心力衰竭 临床效果 Levosimendan Refractory heart failure Clinical effect
  • 相关文献

参考文献5

二级参考文献41

共引文献36

同被引文献21

  • 1杨跃进,尹栋,黄洁.心力衰竭的进展 (16)难治性心力衰竭的治疗原则和措施(续11)[J].中国循环杂志,2007,22(4):243-245. 被引量:7
  • 2Roger VL. Epidemiology of heart failure [ J ]. Circ Res, 2013,113 (6) : 646 - 659.
  • 3Jhund PS, Macintyre K, Simpson CR, et al. Long-term trends in first hos- pitalization for heart failure and subsequent survival between 1986 and2003 : a population study of 5,1 million people [ J ]. Circulation, 2009, 119(4) :515 -523.
  • 4Goldberg R J, Spencer FA, Farmer C, et al. Incidence and hospital death rates associated with heart failure :a community-wide perspective [ J ]. Am J Med,2005,118(7) :728 -734.
  • 5Bleumink GS, Knetsch AM, Suturkenboom MC, et al. Quantifying the heart failure epidemic : prevalence, incidence rate ,lifetime risk and prog- nosis of heart failure the rotterdam study [ J ]. Eur Heart J, 2004,25 (18) :1614 -1619.
  • 6Burger A J, Horton DP, LeJemtel T, et al. Effect of nesiritide ( B-typena- triuretic peptide) and dobutamine on ventricular arrhythmias in the treat- ment of patients with acutely decompensated congestive heart failure: the precedent study[ J]. Am Heart J ,2002,144 : 1102 - 1108.
  • 7Rognoni A, Lupi A, Lazzero M, et al. Levosimendan : from basic science to clinical trials [ J ]. Recent Pat Cardiovasc Drug Discov, 2011,6 : 9 - 15.
  • 8Kasikcioglu HA, Uyarel H,Tartan Z, et al. Do calcium sensitizers affect fight ventricular functions in patients with chronic heart failure? [ J ]. Int J Cardio1,2007, ( 118 ) :246 - 248.
  • 9Samimi FS, Garcia-Gonzlez MJ, Domfnguez-Rodrtguez A, et al. Effects of levosimendan versus dobutamine on long-term survival of patients with cardiogenic shock after primary coronary angioplasty[ J]. Int J Car- dio1,2008, ( 127 ) :284 - 287.
  • 10钱俊峰,姜红,葛均波.我国慢性心力衰竭流行病学和治疗现状[J].中国临床医学,2009,16(5):700-703. 被引量:107

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部