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基于sub-tile的对称有界DNA结构自组装及应用 被引量：1

DNA Self-assembly and Application on Symmetric and Bounded DNA Structure Based on Sub-tile
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摘要 使用一种基于DNA sub-tile的自组装策略,通过模块化的方式灵活构建多种刚性DNA tile,同时利用DNA tile的对称性,创建多种有限尺寸,空间可寻址的纳米网格结构,并阐述其可能在癌症治疗中作为小分子纳米药物颗粒运载工具,实现定向给药的潜在应用. DNA self-assemble strategy based on a special DNA sub-tile was used, and a variety of rigid DNA tiles was created by the modular way. At the same time, a variety of limited and addressable nanomesh structure was created with the symmetry of DNA tiles. The small molecular nano particles could be used as drug carriers in the treatment of cancer, and the potential application of directional drug delivery might be possible
作者 黄春 吴艳敏 姚莉娜 张勋才 王延峰 崔光照
机构地区 郑州轻工业学院电气信息工程学院
出处 《郑州大学学报（理学版）》 CAS 北大核心 2014年第3期102-106,共5页 Journal of Zhengzhou University:Natural Science Edition
基金 国家自然科学基金资助项目 编号61070238 61272022 U1304620 河南省基础与前沿技术研究计划项目 编号122300413211 132300410183 河南省创新型科技人才队伍建设工程支持项目 编号124200510017 郑州市科技人才队伍建设计划(科技领军人才)项目 编号131PLJRC648 河南省教育厅科学技术研究重点项目 编号13A413371
关键词 DNA tile自组装 有限尺寸 可寻址 药物运载 sub-tile DNA self-assembly finite size addressable drug delivery
分类号 TP309 [自动化与计算机技术—计算机系统结构] TP18 [自动化与计算机技术—控制理论与控制工程]
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参考文献13

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二级参考文献21

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共引文献2

同被引文献5

  • 1WINFREE E, I.IU F, WENZLER L A, et al. Design and self-assembly of two-dimensional DNA crystals[J]. Nature 1998, 394(6693):539-544.
  • 2WINFREE E, YANG X, SEEMAN N C. Universal computation via self-assembly of DNA: some theory and experiments[C]. In: Proceedings of the Second Annual Meeting on DNA Based Computers, Providence, 1996.
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  • 5王子成,豆根生,周小刚,叶盟盟.基于DNA链置换反应的自然数素性判定问题研究[J].郑州大学学报（工学版）,2015,36(5):96-100. 被引量：2

引证文献1

郑州大学学报（理学版）
2014年 第3期

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