基于χ~2检验和方差分析的不育症肾虚证证候特征分析

Analysis on Syndromes Characteristics of Kidney-deficiency Related to Barrenness Based on χ~2-test and Variance Analysis

目的通过应用χ2检验和方差分析方法研究肾虚型不育症的证候特征。方法通过对404例肾虚型不育症患者进行临床信息资料的采集,应用Epidata 3.02软件对资料进行双人录入和一致性检验,应用SPSS 17.0软件对资料进行χ2检验和方差分析,对不育症肾虚证的证候特征进行分析。结果结合分析两种方法的结果,最终得到肾阴虚证的相关症状包括:面赤、烘热、口干、咽干、心烦、盗汗、潮热、手足心热、大便干结、小便短赤、遗精;肾阳虚的相关症状包括:神疲、乏力、面色晄白、面色少华、纳差、畏寒、肢冷、气短、大便溏、小便清、尿频、夜尿频多;肾精亏虚证的相关症状包括:发焦/发白/发脱、齿摇/齿脱、健忘、反应迟钝、眩晕、骨软、生长发育迟缓;肾阴虚证与肾精亏虚证的共同症状包括:耳鸣、多梦;肾阳虚证与肾精亏虚证的共同症状包括:面色苍白、口唇淡白、腰膝酸软、性欲减退、阳痿;肾虚三证共有的症状为:失眠;肾虚三证间均不典型的症状包括:表情呆滞、面色萎黄、耳聋、心悸。结论对不育症肾虚证证候特征分析结果符合中医学理论特点;应用以上方法对肾虚证证候特征进行分析是进行深入肾虚证证候学研究的基础。

Objective To study the syndromes characteristics of kidney-deficiency related to bar-renness.Methods The study is to analyze the syndromes characteristics of kidney-deficiency related to barrenness , by clinical information collection of 404 barrenness samples , information entry and consistency check by using Epidata 3.02,χ2-test and variance analysis by using SPSS 17.0.Results 11 items symp-toms related to kidney Yin-deficiency including： Flushing, felt burned, dry mouth, dry throat, vexation, perspire during sleep, hectic fever, feverish palms and soles, dry stool, scanty dark urine, spermatorrhea. 12 items into kidney Yang-deficiency including：Spiritlessness, fatigue, bright-and-pallid complexion, wan complexion, anorexia, chilly, cole limbs, short breath, loose stool, clear urine in large amounts, frequent micturition, night urination.7 items symptoms related to kidney essence-deficiency Brown/White/loose hair, tooth mobility, forgetfulness, lags in response, circumgyration, osteoporosis, hypoevolutism;Tinnitus and dreaminess are marked as the common symptoms of kidney Yin-deficiency and essence-deficiency syn-dromes .Pale complexion , white lips , soreness and weakness of waist and knees , hyposexuality , impotence are marked as the common symptoms of kidney Yang-deficiency and essence-deficiency syndromes .Insom-nia is marked as the common symptom of the three syndromes of kidney-deficiency;Dull expression , Sallow complexion, epicophosis, palpitation are not typical in the three syndromes of kidney-deficiency.Conclu-sion The results of the study on the syndromes characteristics of kidney-deficiency based on χ2-test and variance analysis conform to the theories of TCM .Applying the above methods to analyze the syndromes characteristics of kidney-deficiency is the base of further related study .