多囊卵巢综合征患者内分泌及代谢特征临床研究

Clinical research of polycystic ovary syndrome patients with endocrine and metabolic characteristics

目的对多囊卵巢综合征患者内分泌及代谢特征进行探讨。方法选取2010年1月至2012年12月于本院内分泌门诊就诊的患者50例,根据体质指数将其分为肥胖组与非肥胖组,另选择25例正常女性作为对照组,比较不同分组研究对象之间的血脂和激素水平。结果肥胖组与非肥胖组患者总胆固醇(TC)、甘油三酯(TG)、血清黄体生成素(LH)、胰岛素(INS)、雄激素(T)和泌乳素(PRL)水平均较对照组高,差异均具有显著性(P均<0.05)。结论多囊卵巢综合征患者内分泌及代谢紊乱,其中肥胖患者较非肥胖患者在该问题上表现更为突出,为此应针对此特点采取适当的措施,及早进行防治,避免更多的并发症发生。

Objective To explore the endocrine and metabolic characteristics of patients with polycystic ovary syndrome. Method Chose 50 patients from January 2010 to December 2012 in our hospital endocrine clinic, and divided them into index obese and non-obese group according to their obesity, then chose 25 cases of normal women as control group, compared blood lipid and hormone levels between different groups. Result There were significant differences between different groups, the total cholesterol （TC）, triglyceride （TG）, luteinizing hormone （LH）, insulin （INS）, testosterone （T） and prolactin （PRL） of obese and non-obese group were higher than the control group （Pan 〈 0.05）. Conclusion The patients of polycystic ovary syndrome had endocrine and metabolic disorder, the obese patients of the issue is prominent than non-obese patients, therefore we should take corresponding measures in view of this characteristic, and take some early prevention, then we can avoid the occurrence of more complications.