原发性癫痫情绪识别能力的研究

A study on emotion recognition in patients with idiopathic epilepsy

目的 研究原发性癫痫患者情绪加工和社会认知功能,并探讨其相关影响因素.方法 经神经心理学背景测试后对70例不同脑区痫样放电的原发性癫痫患者和153例健康对照进行眼区基本情绪（喜、怒、悲、恐、厌、惊）和复杂情绪识别评分比较.结果 原发性癫痫组在六种眼区基本情绪识别正确数、总情绪识别正确数及眼区复杂情绪识别正确数[分别喜（19.3±2.0）分、怒（17.9±2.0）分、悲（18.1±2.3）分、恐（16.4±1.9）分、厌（17.6±2.1）分、惊（18.3±1.5）分、总基本情绪（107.7±8.1）分、复杂情绪（23.3±4.2）分]上均显著低于健康对照组[分别喜（19.9±0.2）分、怒（18.9±1.0）分、悲（19.2±1.0）分、恐（17.6±1.3）分、厌（18.6±1.2）分、惊（19.1±1.1）分、总基本情绪（113.4±3.4）分、复杂情绪（27.1±2.8）分],差异均有统计学意义（均P＜0.05）;在男女性别判断任务上与健康对照组差异无统计学意义（P＞0.05）;癫痫组眼区基本和复杂情绪识别得分之间存在正相关（r=0.444,P=0.000）,基本情绪识别得分与正序、逆序数字广度得分正相关（P＜0.05）,复杂情绪识别与逆序数字广度、Stroop效应相关（P＜0.05）,同时基本和复杂情绪都与贝克抑郁评分和汉密尔顿焦虑评分负相关（均P＜0.05）.结论 原发性癫痫病人存在情绪加工和心理理论受损,执行功能和焦虑抑郁水平可能是影响社会认知能力的因素.

Objective To investigate the abilities of emotion recognition and social cognition in patients with idiopathic epilepsy and further explore the factors related to the impairments.Methods After 24-hour EEG monitoring,70 people with idiopathic epilepsy were administered with a neuropsychological battery for basic cognitive assessment and then were tested with the Eye Basic Emotion Discrimination Task （EBEDT） and the Eye Complex Emotion Discrimination Task （ECEDT）.Results Compared with health controls,people with epilepsy got significantly lower score in recognizing happy （19.3±2.0 vs 19.9±0.2）,angry （17.9±2.0 vs 18.9±1.0）,sadness （18.1±2.3 vs 19.2±1.0）,fear （16.4±1.9 vs 17.6±1.3）,disgust （17.6±2.1 vs 18.6±1.2） and surprise （18.3±1.5 vs 19.1±1.1） （P＜0.05,respectively）,as well as complex emotions （（23.3±4.2） vs （27.1±2.8）,P＜0.05）.There was no significant difference between the two groups in gender recognition （P＞0.05）.Significant positive correlation was found between the total score of basic emotions and the mind reading （r=0.444,P=0.000） in the patient group.Correlation analysis revealed significant relation between the total correct number of emotion recognition and the level of anxiety,depression and the executive function in epilepsy group （P＜0.05,respectively）.Significant associations were found between the ECEDT and the Digital Span test,the Stroop test,Beck Depression Index and Hamilton Anxiety Scale （P＜0.05,respectively）.Conclusion People with epilepsy have general impairments of emotion recognition and theory of mind,the impairments may be associated with the state of mood disorder and the weakened executive function.