同期介入治疗冠心病合并锁骨下动脉硬化闭塞症研究

Application of simultaneous interventional therapy in patients combined with coronary artery disease and subclavian arteriosclerosis obliterans

目的评价同期介入治疗冠心病合并锁骨下动脉硬化闭塞症的疗效和安全性。方法于2008年1月至2012年12月,对16例冠心病合并锁骨下动脉硬化闭塞症(动脉管腔狭窄至少70%)确诊患者同期行锁骨下动脉及冠状动脉介入治疗,先行球囊血管成形术,再植入支架。在术后6个月和12个月随访时,分别进行彩色超声和血管造影检查,评估再狭窄情况和临床疗效。结果 16例患者共计38处动脉狭窄病变,均成功进行了经皮介入治疗,无严重并发症发生。术后彩色超声及血管造影检查均未见动脉管腔再狭窄。结论采用同期介入治疗的方法治疗冠心病合并锁骨下动脉硬化闭塞症,具有微创、效果好、并发症少等优点,可作为临床重要的治疗方法。

Objective To evaluate the therapeutic effects and safety of simultaneous interventional therapy in patients combined with coronary artery disease （CHD） and subclavian arteriosclerosis obliterans （SAO） .Methods From January 2008 to December 2012 ,a total of 16 patients combined with CHD and SAO （degree of stenosis at least 70% ） were enrolled and treated with simultaneous interventional therapy ,including balloon angioplasty and stent im-plantation .Color ultrasound and angiography examination were performed at 6 months and 12 months after treatment respectively to evaluate restenosis and therapeutic effects .Results Simultaneous transcatherter therapy was success-fully performed in all 16 patients ,including a total of 38 lesions ,and no serious concurrent symptoms was found . Restenosis of artery was not found by postoperative color ultrasound and angiography examination .Conclusion Sim-ultaneous transcatheter therapy might be minimally invasive ,effective and with fewer complications in the treatment of CHD combined with SAO ,which could be an important treatment method .