摘要
设计合成了16个新型的含哌嗪的吡唑酰胺衍生物,所有化合物结构经1 H NMR、13C NMR、IR和元素分析表征.初步生物活性测试表明,在试验浓度下,部分目标化合物表现出一定的抗菌活性和较好的抗TMV活性.
Sixteen novel pyrazole amide derivatives containing piperazine moiety were designed and synthesized.All the compounds were characterized by 1 H NMR,13 C NMR,IR spectra and elemental analysis.The preliminary bioassay indicated that some of the title compounds showed certain antifungal and anti-TMV activity.
出处
《分子科学学报》
CAS
CSCD
北大核心
2014年第4期273-279,共7页
Journal of Molecular Science
基金
国家自然科学基金资助项目(20442003)
关键词
哌嗪
吡唑酰胺
合成
生物活性
piperazine
pyrazole amide
synthesis
bioactivity
