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高龄患者体外受精-胚胎移植(IVF-ET)不同促排卵方案的临床分析 被引量：13

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摘要 目的比较38-45岁高龄患者应用不同促排卵方案行体外受精-胚胎移植(IVF-ET)治疗的结局。方法回顾性分析2011年6月-2012年6月于我院辅助生殖中心行IVF-ET治疗的327例高龄患者的资料,按其促排卵方法分为3组:A组(短方案组,n=148),B组(拮抗剂方案组,n=63),C组(微刺激方案组,n=116)。比较各组的促排卵治疗结果和临床结局。结果 3组患者的Gn(促性腺激素)使用天数、Gn支数、子宫内膜厚度两两比较显示:B组最高,A组次之,C组最低,A、B两组间无显著性差异(P>0.05),C组与A、B两组分别比较均有显著性差异(P<0.05)。获卵数、移植胚胎数、受精率比较显示:A组最高,B组次之,C组最低,A组与B、C两组分别比较均有显著性差异(P<0.05),B、C组间比较无显著性差异(P>0.05)。周期取消率C组最高,B组次之,A组最低,C组与A、B两组分别比较均有显著性差异(P<0.05)。宫外孕率A组最高,C组次之,B组最低,B组与A、C两组分别比较均有显著性差异(P<0.05)。结论 3组患者的获卵数、妊娠率、种植率均低,流产率无显著性差异,但C组Gn天数Gn支数以及移植胚胎数最低(P<0.05),说明微刺激方案对卵巢的刺激轻,干扰少,费用低,可作为高龄妇女行IVF-ET治疗的首选方案。
作者 苏琼 伍琼芳 田莉峰 李游
机构地区 江西省妇幼保健院辅助生殖中心
出处 《江西医药》 CAS 2014年第8期723-725,共3页 Jiangxi Medical Journal
关键词 高龄 体外受精-胚胎移植 促排卵方案 短方案 拮抗剂方案 微刺激方案
分类号 R711.7 [医药卫生—妇产科学]
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参考文献9

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二级参考文献1

共引文献22

同被引文献68

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引证文献13

二级引证文献69

江西医药
2014年 第8期

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