经尿道不同切除方式治疗非肌层浸润性膀胱癌患者的疗效观察

Effect observation on different transurethral resection patterns for treating patients with non-muscle invasive bladder cancer

目的比较2μm激光与双极电刀用于经尿道膀胱肿瘤切除术(TURBT)治疗非肌层浸润性膀胱癌(NMIBC)的安全性及有效性。方法回顾性分析2009年3月至2013年5月接受TURBT治疗的NMIBC患者的临床资料,比较2μm激光组(n=89)与双极电刀组(n=82)在手术时间、并发症、术后住院时间及复发率等方面的差异。结果两组手术时间、术后住院天数及复发率等方面差异无统计学意义(P>0.05)。双极电刀组术中闭孔神经反射(20.7%)和膀胱穿孔(7.3%)的发生率明显高于2μm激光组(P<0.05)。2μm激光组术后膀胱冲洗时间(2.2±1.0)d明显短于双极电刀组(3.1±0.9)d,差异有统计学意义(P<0.05)。结论与双极电刀相比,2μm激光用于TURBT治疗NMIBC,安全、有效、并发症少。

Objective To compare the safety and efficacy of the 2μm laser and the bipolar electrotome used in transurethral re-section of bladder tumor（TURBT）for treating non-muscle invasive bladder cancer（NMIBC）.Methods The clinical data in the pa-tients with NMIBC treated by TURBT in our hospital from March 2009 to May 2013 were retrospectively analyzed.All patients were divided into the 2μum laser group（n=89）and the bipolar electrotome group（n=82）.The operation time,complications,post-operative hospital stay and recurrence rate were compared between the two groups.Results There were no statistically significant differences in the operation time,postoperative hospital stay and recurrence rate between the two groups（P〉0.05）.Compared with the 2 μm laser group,the bipolar electrotome group showed significantly higher occurrence rate of the obturator nerve reflex （20.7%vs.0,P〈0.05）and the bladder perforation（7.3% vs.0,P〈0.05）and longer postoperative bladder irrigation time [（3.1±0.9）d vs.（2.2±1.0）d,P〈0.05],the differences between the two groups had statistical significance.Conclusion Com-pared with bipolar electrotome,the 2μm laser used in TURBT is safe and effective with few complications for treating NMIBC.