熄风止痒汤治疗老年性皮肤瘙痒症50例

XiFeng ZhiYang Tang in Treating 50 Senile Patients with Cutaneous Pruritus

目的:观察熄风止痒汤加减治疗老年性皮肤瘙痒症的临床疗效。方法:将100例老年性皮肤瘙痒症患者随机分为治疗组和对照组各50例。对照组给予左西替利嗪5 mg,1次/d,口服;治疗组在此基础上加用熄风止痒汤,1剂/d,水煎分服。2组均以7天为1个疗程。观察2组治疗前后瘙痒程度、发生频率、持续时间等症状积分的变化情况及临床疗效。结果:治愈率治疗组为50.00%,对照组为32.00%,2组比较有差异有统计学意义(P<0.05)。总有效率治疗组为94.00%,对照组为80.00%,2组比较差异有统计学意义(P<0.05)。瘙痒程度、发生频率、瘙痒面积等症状积分2组治疗后均明显改善(P<0.05),治疗后组间比较差异有统计学意义(P<0.05)。结论:熄风止痒汤加减治疗老年性皮肤瘙痒症临床疗效显著,可较好地改善临床症状。

Objective： To discuss therapeutic effects of modified XiFeng ZhiYang Tang in treating senile patients with cutaneous pruritus. Methods：One hundred patients were randomized into the observation group and the control group, 50 cases each group. The control group were given with levocetirizine, 5mg, once per day, orally;the observation group took XiFeng ZhiYang Tang on the foundation of the treatment administered to the control group, water decocted, one dose each day. Seven days were one course of the treatment. Curative effects and the changes of symptom scales including the degrees of itching, the frequency, duration and others were observed before and after treating. Results：Clinical cure rate of the observation group was 50.00%, higher than 32.00%of the control group with significant difference （P〈0.05）. Total effective rate of the treatment group was 94.00%, superior to 80.00%of the control group with notable difference （P〈0.05）. Symptom scales including the degrees of itching, frequency, itching areas were improved obviously after treating （P〈0.05）, the difference demonstrated statistical meaning between both groups after treating （P〈0.05）. Conclusion： Modified XiFeng ZhiYang Tang could obtain better effects in treating senile patients with cutaneous pruritus, and it could improve clinical symptom.