安肠止痛组方联合曲美布汀治疗腹泻型肠易激综合征78例

Treating 78 Cases of Irritable Bowel Syndrome of Diarrhea Pattern by AnChang ZhiTong Prescription and Trimebutine

目的:观察安肠止痛组方联合曲美布汀治疗腹泻型肠易激综合征(irritable bowel syndrome,IBS)的临床疗效。方法:将226例腹泻型IBS患者随机分为3组。西医组77例采用曲美布汀治疗,中医组71例采用安肠止痛组方治疗,中西医结合组78例,采用安肠止痛组方联合曲美布汀治疗。3组均以4周为1个疗程。结果:总有效率中西医结合组为89.74%,中医组为74.65%,西医组为58.44%,3组比较无明显差异(P>0.05)。BSS评分3组治疗后均明显降低(P<0.05),中西医结合组优于中医组及西医组(P<0.05),中医组优于西医组(P<0.05)。结论:中西医结合治疗腹泻型IBS疗效优于单纯中医或单纯西医治疗。

Objective： To discuss curative effects of AnChang ZhiTong prescription and trimebutine in the treatment for irritable bowel syndrome of diarrhea pattern （IBS-D）. Methods：All 226 cases were randomly allocated to three groups. Seventy-seven cases of western medicine group were treated with trimebutine, 71 cases of herbs group took AnChang ZhiTong prescription, 78 cases of integrative medicine group were given with both, one course of the treatment were four weeks. Results：Total effective rates of integrative medicine group, herbs group and west-ern medicine group were 89.74%, 74.65%and 98.44%, there were insignificant differences among three groups （P〉0.05）. 〈br〉 BSS scales of three groups were lowered obviously after treating （P〈0.05）, integrative medicine group was superior to herbs group and western medicine group （P〈0.05）, herbs group was better than western medicine group （P〈0.05）. Conclusion： Therapeutic effects of integrative medicine are superior to only herbs or western medicine in treating IBS-D.