Cirrus HD OCT检测近视眼黄斑中心凹下脉络膜厚度的研究

Subfoveal choroidal thickness measured by Cirrus HD optical coherence tomography in myopia

目的:应用Cirrus HD OCT测量近视眼黄斑中心凹下脉络膜厚度(SFCT),并探讨其与眼轴、等效球镜的关系。方法:纳入正常志愿者70例133眼,分为正视眼组、低度近视组、中度近视组及高度近视组。应用Cirrus HD OCT测量受检者SFCT,并评估其与眼轴、等效球镜的关系。结果:(1)正常人SFCT值为(275.91±55.74)μm,正视眼组、低度近视组、中度近视组及高度近视组SFCT值分别为(290.03±34.82)μm,(287.64±51.51)μm,(274.95±56.83)μm,(248.37±67.98)μm;(2)高度近视眼与正视眼SFCT值相比差异有统计学意义(P<0.05);(3)SFCT与眼轴呈高度线性负相关(P<0.01),SFCT与等效球镜呈高度线性正相关(P<0.01)。结论:SFCT与屈光度有关,且与眼轴呈负相关,与等效球镜呈正相关。

ATM： To measure the subfoveal choroidal thickness（ SFCT） in myopia using Cirrus HD optical coherence tomography（ OCT）, and to explore the relationship between the SFCT, axial length and myopic refractive spherical equivalent. METHODS： One- hundred thirty- three eyes of 70 healthy volunteers were recruited,and were divided into emmetropia group,low-degree myopia,middle-degree myopia and high- degree myopia group. SFCT were measured by Cirrus HD OCT, and the relationship between the SFCT, axial length and myopic refractive spherical equivalent were evaluated.RESULTS： 1） Average SFCT was（ 275.91±55.74） μm in normals,that in emmetropia group,low-degree myopia,middle- degree myopia and high- degree myopia group were（ 290.03± 34. 82） μ m,（ 287. 64± 51. 51） μ m,（ 274. 95 ±56. 83） μ m,（ 248. 37 ± 67. 98） μ m; 2） the SFCT of high-degree myopia group was significant thinner than that of emmetropia group（ P〈0.05）; 3） There was a significant negatives correlation between the SFCT and axial length（ P〈0.01）,a significant positive correlation between SFCT and myopic refractive spherical equivalent（ P〈0.01）.CONCLUSION： the SFCT is inversely correlated with increasing axial length and myopic refractive error.