白内障患者术前角膜内皮与术后视力及眼压的相关性分析

Relationship between postoperative corneal endothelium and postoperative visual acuity,intraocular pressure in cataract patients

目的探讨白内障患者术前角膜内皮情况与术后早期视力及眼压的相关性。方法随机选取在我院2010年6月至2011年5月行白内障超声乳化摘出联合人工晶状体植入术110例术后3d内视力达到0.3以上的年龄相关性白内障患者(术后视力≥0.3组)及31例术后3d内最佳视力不足0.3的年龄相关性白内障患者(术后视力<0.3组),分别按手术前后眼压变化分为眼压升高组及眼压不升高组,对所有患者术前中央角膜厚度(central corneal thickness,CCT)、角膜内皮细胞密度(endothelial cell density,CD)及六角形细胞百分数(the percentage of hexagonal cells,HEX)进行统计学对比分析。结果术后视力达到0.3和不足0.3组比较、亚组间比较,中央角膜厚度及六角形细胞百分数差异均无统计学意义(均为P>0.05);视力不足0.3的眼压升高与不升高患者比较,角膜内皮细胞密度差异有统计学意义(P=0.024)。结论白内障患者术后早期视力与角膜内皮细胞情况无明显相关关系;角膜内皮细胞密度对维持白内障术后眼压的稳定性有一定作用。

Objective To explore the relationship between postoperative corneal endothelium and postoperative visual acuity, intraocular pressure in cataract patients. Methods A total of 141 age-related cataract patients underwent phacoemulsification and intraocular lens implantation from June 2010 to May 2011 in our hospital were chosen,in which the visual acuity within 3 days after operation were more than 0.3 in 110 cases （more than 0.3 group） ,less than 0.3 in 31 cases （less than 0.3 group） ,all patients were divided into two groups based on postoperative intraocular pressure （IOP） ： high IOP group and normal IOP group, the preoperative central corneal thickness, corneal endothelial cell density and percentage of hexagonal cells were compared and analyzed. Results There was no statistical difference in central corneal thickness and percentage of hexagonal cells between postoperative visual acutity more than 0. 3 groupand less than 0.3 group, and between each subgroup （ all P 〉 0.05 ）, there was statistical difference in corneal endothelial cell density between high IOP group and normal lOP group in patients with postoperative visual acuity less than 0. 3 （ P = 0. 024）. Conclusion The early postoperative visual acuity has no relationship with corneal endothelial cells in cataract patients, and corneal endothelial cell density plays the certain role in maintaining the stability of postoperative intraocular pressure.