溶栓疗法结合血塞通治疗老年急性心肌梗死临床观察

Clinical Observation of Thrombolysis Therapy and Luotail for Acute Myocardial Infarction in Old Patients

观察溶栓与非溶栓疗法合并血塞通治疗老年性急性心肌梗死的疗效 ,对 48例老年AMI以溶栓治疗 7天后 ,有 2 7例用血塞通治疗 ;6 2例非溶栓治疗 7天后 ,有 33例合用血塞通治疗 ,均为 14～ 17天。结果 :合用血塞通治疗包括溶栓和非溶栓病例 ,住院期心肌再梗死率 (8%)低于非血塞通治疗的病例 (2 4%) (P <0 .0 5 ) ;AMI后心绞痛伴ST T缺血性改变发生率 ,血塞通治疗为 13%,非血塞通治疗为 36 %(P <0 .0 1)。血塞通治疗后血黏度和C反应蛋白下降明显。提示老年AMI患者无论溶栓与否 ,合并应用血塞通可减少住院期心肌再梗死率和AMI后心绞痛伴ST T缺血性改变发生率。

To observe the clinical efficacy of thrombolysis therapy and luotail in the treatment of acute myocardial infarction (AMI) in the old people,48 cases were treated by thrombolysis therapy for 7 days and 27 cases of them were then additionally given luotail for 14～21 days; 62 cases were treated by non-thrombolysis therapy and 33 cases of them were then additionally given luotail.Results:The infarction rate in patients on luotail was 8%,lower than 24% in patients not on luotail (P<0.05);the rate of angina pectoris with ST-T ischemic change was 13% in patients on luotail and 32% in those not on luotail (P<0.01);the blood viscosity and C reaction protein dropped obviously.It is revealed in old patients that luotail with thrombolysis therapy or not can reduce the re-infarction rate and morbidity of angina pectoris and ST-T ischemic change.