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药物超敏反应综合征一例 被引量:2

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摘要 患者女,20岁。因发热6d,躯干红斑伴痒5d,加重4d,于2013年10月913入院。患者入院前6d因发热、咽痛服用复方氨基比林2片。服药后1d躯干出现绿豆至花生米大红斑,伴痒。就诊前4d,皮损迅速波及全身皮肤黏膜。
出处 《国际皮肤性病学杂志》 2014年第5期339-339,共1页 International Journal of Dermatology and Venereology
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  • 1Saraya T, Mikoshiba M, Kamiyama H, et al: Evidence for reactivation of human herpesvirus 6 in generalized lymphadenopathy in a patient with drug-induced hypersensitivity syndrome[J].J Clin Microbiol,2013;51(6):1979-1982.
  • 2Melsom R: Familial hypersensitivity to allopurinol with subsequent desensitization[J].Rheumatology (Oxford), 1999; 38( 12): 1301.
  • 3Tassaneeyakul W, Jantararoungtong T, Chen P, et al: Strong association between HLA-13*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population[J].Pharmacogenet Genomics,2009; 19(9) :704 - 709.
  • 4Criado P R, Avancini J, Santi C G, et al. Drug reaction with eosinophilia and systemic(DRESS) : a complex interaction of drugs,viruses and the immune system[J]. Isr Med Assoc J 2012,14(9) : 577-582.
  • 5Halevy S, Ghislain P D, Mockenhaupt M, et al. Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal neerolysis in Europe and Israel[J]. J Am Acad Dermatol, 2008,58 (1) : 25-32.
  • 6Melsom R D. Familial hypersensitivity to allopurinol with subsequent desensitization[J]. Rheumatology(Oxford), 1999, 38(12) : 1301.
  • 7Tassaneeyakul W, Sjantararoungtong T, Chen P, et al. Strong association between HLA-B5801 and allopurinol-induced Ste- vens-Johnson syndrome and toxic epidermal necrolysis in a Thai population[J]. Pharmacogenet Genomics, 2009,19 (9) : 704-709.
  • 8Kim S H,Ye Y M,Palikhe N S,ct al. Genetic and ethnic risk factors associated with drug hypersensitivity[J]. Curr Opin Allergy Clin Immunol, 2010,10 (4) : 280 -290.
  • 9兰菲,耿龙,毕桂姣,徐媛媛,尹璐,姚放.药物超敏反应综合征1例[J].中国皮肤性病学杂志,2012,26(5):460-461. 被引量:4
  • 10王松,尉晓冬,许爱娥,袁卫如,施若非,郑捷.药物超敏反应综合征后发生白癜风二例[J].中华皮肤科杂志,2012,45(6):447-448. 被引量:5

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