颈动脉粥样硬化兔造模的常用方法

Commonly Used Methods to Build Carotid Atherosclerosis Models of Rabbits

兔颈动脉粥样硬化狭窄模型制备的方法很多,包括内膜空气干燥法、球囊损伤法、颈总动脉套环法、直流电刺激颈动脉外膜法、幽门螺杆菌感染法、显微缝合法、放射处理法、液氮损伤法、化学烧灼法等,不同的造模方式颈动脉粥样硬化狭窄形成的机制及病理特点各不相同。本文重点介绍颈动脉粥样硬化兔模型的制作方法及其优、缺点。

There are many methods to build carotid atherosclerosis models of rabbits. For example, air drying, balloon injury, silicone collar, electrical stimuli, microsurgical suture, Helicobacter pylori infection, radiation treatment, liquid nitrogen damage method, chemical burning method, etc. Different ways of building carotid atherosclerotic stenosis have different mechanism and pathological characteristics. This article focuses on the methods of making the carotid ather- osclerotic models and their advantages and disadvantages.