间苯三酚联合倍美力软膏在绝经取环中的应用

Application of intravenous injection of phloroglucinol combined premarin ointment in postmenopausal women with the ointment intrauterine device

目的观察静脉注射间苯三酚联合倍美力阴道用软膏在绝经后妇女宫内节育器(IUD)取出术中的临床疗效。方法将100例需要取宫内节育器的绝经后妇女随机分为2组。观察组50例,术前7 d开始应用倍美力阴道用软膏0.5 g,2次/d,术前15 min静脉注射间苯三酚40 mg;对照组50例,不用任何药物,常规取宫内节育器。观察患者疼痛程度、宫颈软化程度及一次性取出宫内节育器的成功率等。结果观察组患者疼痛程度、宫颈软化程度及一次性取出宫内节育器的成功率均优于对照组,差异有统计学意义(P<0.05)。结论间苯三酚联合倍美力软膏用于绝经后宫内节育器取出术,取器的临床效果好,宫颈软化确切,操作简便,不良反应少,取器成功率高,值得临床推广应用。

Objective To observe the intravenous injection of phloroglucinol combined times mei-li vagina in postmenopausal women with the ointment intrauterine device （IUD）, use the clinical curative effect. Methods 100 patients needed to take the intrauterine device in postmenopausal women were randomly divided into two groups. Observation group of 50 eases, preoperative 7 days start application times mei-li ointment twice 0.5 g/day for vagina before 15 min 40 mg intrave- nous injection of phloroglucinol. The control group of 50 cases, no drugs, conventional intrauterine device. The pain degree,the cervix softening degree were observed and success rate of one-time out intrauterine device was recorded. Results The observation group of patients pain degree, the cervix softening and the success rate of one-time out intrauterine device were superior to control group, the difference was statistically significant （ P 〈 0.05 ）. Conclusion Phloroglucinol combined premarin ointment for menopause in synthetic harem, had take good clinical effect and the cervix softening exact, simple operation,less adverse reaction, with a high success rate, which was worthy of clinical popularization and application.