膀胱肿瘤术后采用吡柔比星膀胱灌注预防术后复发的护理

Nursing intervention for patients undergoing pirarubicin bladder perfusion after bladder tumor surgical treatment

目的探讨膀胱肿瘤术后采用吡柔比星(THP)进行膀胱灌注预防术后复发的护理要点。方法采集86例膀胱恶性肿瘤病患资料,从膀胱肿瘤术后2周开始按继续药物治疗方案进行膀胱腔内灌注,每次灌注使用吡柔比星30 mg,每周1次,连续灌注8周,以后每月灌注1次,连续灌注8个月;灌注期间对病患加强护理措施,并在3年内密切随访。结果在完成1个疗程的吡柔比星膀胱灌注之后,随访3年发现,患者无瘤生存率达69.77%以上。结论膀胱肿瘤术后,采用吡柔比星膀胱灌注能确实有效地预防术后复发,而在灌注期间重视观察病患病情,关注药物毒副作用,加强相关护理措施及心理辅助是确保灌注疗效的重要环节,值得高度重视。

Objective To explore the nursing points for patients undergoing pirarubicin bladder perfusion after bladder tumor surgical treatment. Methods Total 86 cases of bladder tumor received pirarubicin bladder perfusion after surgical treatment from the second week. The dose of pirarubiein was 30 mg each time for 8 weeks, once a week, and then once a month for 8 months. The enhanced nursing quality management was performed. All patients were followed up closely for 3 years. Results The follow up of 3 years showed that the disease-free survival rate of patients receiving a course of pirarubicin bladder perfusion was 69.77%. Conclusion The pirarubicin bladder perfusion after the surgical treatment can effectively prevent the postoperative recurrence of bladder tumor. The attention to patients＇ condition and drug toxicity during perfusion, careful nursing care and psychological aid can improve the efficacy of bladder perfusion.