炎琥宁联合维生素K_4治疗小儿秋季腹泻的效果观察

Effect observation of Yanhuning combined with vitamin K_4 treating infantile autumn diarrhea

目的：观察炎琥宁联合维生素K4治疗小儿秋季腹泻的临床效果。方法选取2013年6月～2014年6月本院儿科收治的腹泻患者160例，随机分为观察组和对照组，每组各80例。观察组给予炎琥宁静脉滴注联合维生素K4口服治疗，对照组给予利巴韦林静脉滴注。7 d后观察两组患者的总有效率、退热时间、止泻时间、临床症状改善时间等。结果观察组中显效60例，有效12例，无效8例，总有效率为90.0%，对照组中显效41例，有效15例，无效24例，总有效率为70.0%，观察组的总有效率显著高于对照组，退热时间、止泻时间、临床症状改善时间明显短于对照组（P〈0.05）。结论炎琥宁联合维生素K4治疗小儿秋季腹泻的临床效果显著，值得临床推广应用。

Objective To observe the clinical effect of Yanhuning combined with vitamin K4 treating infantile autumn diarrhea. Methods 160 children with autumn diarrhea treated in department of paediatrics of our hospital from June 2013 to June 2014 were selected and they were randomly divided into the observation group （n=80） and the control group （n=80）.The observation group was treated with Yanhuning for for intravenous drip combined with oral vitamin K4, the control group was treated with ribavirin for intravenous drip.After 7 days,the total effective rate,antifebrile time,antidiarrheal time and clinical symptoms improved time in the two groups were observed. Results In the observation group,60 cases were markedly effective,12 cases were effective,8 cases were ineffective,the total effective rate was 90.0% while in the control group,41 cases were markedly effective,15 cases were effective,24 cases were ineffective,the total effective rate was 70.0%,the total effective rate of the observation group was significantly higher than that of the control group,antifebrile time,antidiarrheal time and clinical symptoms improved time in the observation group were obviously shorter than those in the control group （P〈0.05）. Conclusion The clinical effect of Yanhuning combined with vitamin K4 treating infantile autumn diarrhea is significant,and it is worthy of clinical promotion and application.