熊去氧胆酸治疗急性病毒性肝炎早期疗效观察

Early Effi cacy Observation of Ursodeoxycholic Acid in Treatment of Acute Viral Hepatitis

目的探讨熊去氧胆酸治疗急性病毒性肝炎早期临床效果,以期提高临床诊治水平。方法选取2010年1月—2014年1月间收入的60例急性病毒性肝炎患者为研究对象,随机分成2组,对照组采用门冬氨酸钾镁针剂治疗,观察组则采用熊去氧胆酸治疗,观察治疗后临床效果。结果对照组治愈率36.67%,总有效率70%;观察组治愈率56.67%,总有效率86.67%;两组组比较差异有统计学意义(P<0.05)。结论熊去氧胆酸能有效提高急性病毒性肝炎早期临床效果。

Objective To Investigate the early efficacy observation of ursodeoxycholic acid in treatment of acute viral hepatitis. Methods 60 cases with acute viral hepatitis from Jan. 2010 to Jan. 2014 were chosen and randomly divided into two groups. The control group were given potassium magnesium aspartate injection, and the observation group were given ursodeoxycholic acid, the clinical efficacy of two groups after treatment were observed. Results The cure rate of control group was 36.67%, total rate was 70%; while in the observation group was 56.67%, total rate was 86.67%; the differences of two groups had statistically significance （P〈0.05）. Conclusion Ursodeoxycholic acid could improve the early clinical efficacy of acute viral hepatitis.