期刊文献+

替罗非班在缺血性卒中溶栓和血管内治疗中的应用 被引量:11

Appfication of firofiban in ischemic stoke thrombolysis and endovascular therapy
原文传递
导出
摘要 血小板糖蛋白(phteIetglycoprotein,GP)Ⅱb/Ⅲa受体拮抗药替罗非班已广泛应用于急性冠状动脉综合征(acutecoronarysyndrome,ACS)和经皮冠状动脉介入(percutaneoustransluminalcoronaryintervention,PCI)的治疗。文章介绍了替罗非班的作用机制以及在缺血性卒中静脉溶栓、动脉溶栓、血管内治疗中的应用,强调了替罗非班在急诊脑血管成形术中应用的安全性和有效性。 Tirofiban, a platelet glycoprotein (GP) Ⅱb/Ⅲa receptor antagonist has been widely used in the treatment of acute coronary syndrome (ACS) and percutaneous transluminal coronary intervention. This article introduces the mechanism of action of tirofiban and its application in intravenous thrombolysis, intra- arterial thrombolysis, and endovascular therapy in ischemic stroke, emphasizing the safety and effectiveness of tirofiban in the application of the emergency cerebral angioplasty.
出处 《国际脑血管病杂志》 北大核心 2014年第8期620-624,共5页 International Journal of Cerebrovascular Diseases
关键词 卒中 脑缺血 抗血小板聚集药 血小板糖蛋白GPⅡb—Ⅲa复合物 替罗非班 血栓溶 解疗法 血栓切除术 支架 血管成形术 Stroke Brain Ischemia Platelet Aggregation Inhibitors Platelet Glycoprotein GP Ⅱb/Ⅲa Complex Tyrosine tirofiban Thrombolytic Therapy Thrombectomy SteMs Angioplasty
  • 相关文献

参考文献44

  • 1Kim JII, Jeong MH, Rhew JY, et al. Long-term clinical outcomes of platelet glycoprotein Ⅱb/Ⅲa inhibitor combined with low molecular weight heparin in patients with acute coronary syndrome. Circ J, 2005, 69: 159-164.
  • 2Dubois CL, Behnans A, Granger CB, et al. ASSENT -3 Investigators. Outcome of urgent and elective percutaneous coronary interventions after phannacologic reperfusion with tenecteplase combined with unfractionated heparin, enoxaparin, or abciximab. J Am Coil Cardiel, 2003,42: 1178-1185.
  • 3Assessment of the Safety and Efficacy of a New Treatment Strategy with Percutaneous Coronary Intervention (ASSENT-4 PCI) investigators. Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST -segment elevation acute myocardial infarction (ASSENT -4 PCI): randomised trial. Lancet, 2006, 367: 569-578.
  • 4Pfefferkorn T, Holtmannspotter M, Schmidt C, et al. Drip, ship, and retrieve: cooperative recanalization therapy in acute basilar artery occlusion. Stroke, 2010, 41: 722-726.
  • 5Bansal S, Sangha KS, Khatri P. Drug treatment of acute ischemic stroke. Am J Cardiovasc Drugs, 2013,13: 57-69.
  • 6Hacke W, Kaste M, B1uhrnki E, et al. ECASS Investigators. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med, 2008, 359: 1317-1329.
  • 7Pancioli AM, Broderick J, &ott T, et al. CLEAR Trial Investigators. The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke, 2008, 39: 3268-3276.
  • 8Siebler M, Hennerici MG, Schneider D, et al. Safety of Tirofiban in acute Ischemic Stroke: the SaTIS trial. Stroke, 2011, 42: 2388-2392.
  • 9Liebeskind DS, Pollard JR, Schwartz ED, et al. Vertebrobasilar thrombolysis with intravenous tirofiban: case report. J Thromb Thrombolysis, 2002, 13: 81-84.
  • 10Philipps J, Thomalla G, Glahn J, et al. Treatment of progressive stroke with tirofiban-experience in 35 patients. Cerebrovasc Dis, 2009, 28: 435-438.

同被引文献101

  • 1谭燕,刘鸣,王清芳,阳清伟,谈颂,吴波.脑卒中急性期血压与预后的关系[J].中华神经科杂志,2006,39(1):10-15. 被引量:84
  • 2李焰生.中国后循环缺血的专家共识[J].中华内科杂志,2006,45(9):786-787. 被引量:1142
  • 3RBischof D, Dalbert S, Zollinger A, et al. Thrombelastography in the surgical patient[ J]. Minerva Anestesiol, 2010, 76:131-137.
  • 4Afshari A, Wikkelso A, Brok J, et al. Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion [ CD ]. Cochrane Database Syst Rev, 2011, (3): CD007871.
  • 5da Luz LT, Nascimento B, Rizoli S. Thrombelastography (TEG): practical considerations on its clinical use in trauma resuscitation[ J ]. Scand J Trauma Resusc Emerg Med, 2013, 21:29.
  • 6Ganter MT, Hofer CIL Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices [J]. Anesth Analg, 2008, 106: 1366-1375.
  • 7Reikvam H, Steien E, Hauge B, et al. Thrombelastography [ J ]. Transfus Apher Sci, 2009, 40:119-123.
  • 8Bochsen L, Wiinberg B, Kjelgaard-Hansen M, et al. Evaluation of the TEG platelet mapping assay in blood donors [ J]. Thromb J, 2007, 5 : 3.
  • 9Hobson AR, Agarwala RA, Swallow RA, et al. Thrombelastography: current clinical applications and its potential role in interventional cardiology[J]. Platelets, 2006, 17: 509-518.
  • 10Lev EI, Patel RT, Maresh KJ, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance [ J ]. J Am Coll Cardiol, 2006, 47: 27- 33.

引证文献11

二级引证文献160

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部