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右美托咪定对心肌梗死围PCI手术期临床镇静疗效观察 被引量:5

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摘要 目的观察右美托咪定对AMI患者行PCI治疗围术期临床镇静疗效。方法将200例急性初发ST段抬高型AMI患者随机分为研究组和对照组各100例。研究组给予右美托咪定镇静,对照组给予吗啡镇静,对比2组PCI术后无/慢复流比例和临床不良事件发生率,对比2组治疗前后肾上腺素(E)和去甲肾上腺素(NE)水平。结果研究组无/慢复流、心脏骤停、再发梗死、短阵室速、心室电风暴及心力衰竭发生率均低于对照组,差异有统计学意义(P<0.05)。2组治疗后NE、E水平均低于治疗前,且研究组低于对照组,差异均有统计学意义(P<0.05)。结论右美托咪定用于急性AMI行PCI治疗围术期能达到良好的镇静、镇痛效果,降低临床不良事件,对心脏起保护作用。
出处 《临床合理用药杂志》 2014年第28期24-25,共2页 Chinese Journal of Clinical Rational Drug Use
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