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三尖瓣反流的外科治疗进展 被引量:2

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摘要 风湿性心脏瓣膜病(风心病)是临床常见病,患者可能继发功能性三尖瓣反流,发病率为25%~30%[1]。早期研究显示,轻度三尖瓣关闭不全在左心瓣膜病变得到纠正,而且术后经过内科药物治疗就可以得到逆转[2]。但实际情况并非如此,许多患者即使在成功的二尖瓣手术后,仍然会出现三尖瓣反流,通常伴有不同程度的右心功能不全,表现为双下肢水肿和腹水,内科药物治疗效果较差,且病情不断进展,甚至需再次进行手术干预,最终抵消了心脏矫治术的临床价值[3-4]。其机制可能为左心瓣膜病变患者的三尖瓣环发生了不可逆性损害,虽然在左心瓣膜术后心排血量增加,压力负荷减少,但扩大的三尖瓣环无法完全恢复正常,并造成右心室、三尖瓣环扩大与三尖瓣反流的恶性循环[5-7],成为风心病瓣膜手术后远期死亡的主要原因之一。
作者 王建宇
机构地区 天津市天津医院
出处 《中国中西医结合急救杂志》 CAS 北大核心 2014年第5期399-400,共2页 Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
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参考文献29

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二级参考文献20

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二级引证文献45

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