深圳部分基层医疗单位临床分离金黄色葡萄球菌及其耐药性

CLINICAL ISOLATION AND DRUG RESISTANCE OF staphylococcus aureus OF BASIC MEDICAL UNITS IN SHENZHEN

目的研究城市基层医疗单位患者送检标本中检出的金黄色葡萄球菌及其耐药性,以便加强社区感染管理。方法采用细菌学鉴定技术和药敏试验方法,对深圳市某医院所属社区健康服务中心患者标本进行了检测与评价。结果从这些基层医疗单位患者送检标本中共检出金黄色葡萄球菌153株,主要分离自痰液,占69.9%;其次是创面分泌物,占20.9%。在153株金黄色葡萄球菌中,耐甲氧西林(MRSA)菌株占24.18%。临床分离的金黄色葡萄球菌对替考拉宁、万古霉素、夫西地酸、呋喃妥因和利福平等抗菌药物全部敏感,对部分临床常用抗菌药物耐药率达到80%以上。结论深圳部分基层医疗单位临床分离金黄色葡萄球菌主要来自痰液标本,MRSA菌株分离率较高,耐药严重。

Objective To study isolation of Staphylococcus aureus and its drug resistance in some basic medical units of Shenzhen, so as to effectively strengthen the management of community - acquired. Methods Bacterial isolation and identification technology and drug sensitive tests were used for the testing and evaluation of the Staphylococcus aureus from the patients samples of the community health centers（CHCs） in a hospital. Results There were 153 strains of Staphylococcus aureus isolated, mainly isolated from sputum, accounting for 69.9%. Secondly from wound secretion, accounting for 20.9%. And the separation rate of MRSA in Staphylococcus aureus was 24. 18%. All the Staphylococcus aureus strains were 100% sensitive to teicoplanin, vancomycin, fusidic acid, furantoin and rifampicin. The drug - resistant rate were above 80. 0% to the other anti - biotics . Conclusion Staphylococcus aureus were mainly isolated from sputum in many basic medical units of Shenzhen, and the separation rates of MRSA are high, while the drug resistance is serious.