纳米炭在胃癌根治术中的临床意义

Clinical value of carbon nanoparticle in gastrectomy of stomach neoplasms

目的 探讨局部注射纳米炭在胃癌根治术中的临床应用价值.方法 将40例胃癌患者术中局部注射纳米炭行胃癌根治术作为试验组,40例胃癌患者行常规胃癌根治术作为对照组,对清扫微小淋巴结的数量及转移微小淋巴结的数量进行对比.结果 试验组和对照组平均每例清扫微小淋巴结数量N1、N2、N3间差异均有统计学意义[（5.120 ±0.455）枚比（2.900 ± 0.245）枚、（3.890±0.367）枚比（1.750±0.256）枚、（1.790±0.224）枚比（0.590±0.054）枚]（P＜0.01）.试验组和对照组平均每例清扫转移微小淋巴结数量N1、N2、N3差异均有统计学意义[（1.090±0.087）枚比（0.430±0.044）枚、（0.550±0.052）枚比（0.340±0.027）枚、（0.410±0.044）枚比（0.130±0.013）枚]（D＜0.05）.两组患者术后并发症、病死率及住院时间比较差异无统计学意义（P＞0.05）.结论 在胃癌根治术中应用纳米炭是一种简单、安全和易行的方法,对常规胃癌根治术有一定的辅助作用.

Objective To evaluate the clinical application value of local injections of carbon nanoparticle in gastrectomy of stomach neoplasms.Methods Forty cases of stomach neoplasms with local injections of carbon nanoparticle in gastrectomy of stomach neoplasms were as experimental group,and 40 cases of stomach neoplasms with conventional gastrectomy of stomach neoplasms were as control group.The number of removed tiny lymph node and transferred tiny lymph node was compared.Results There was significant difference in the average number of removed tiny lymph node N1,N2,N3 between experimental group and control group （5.120 ± 0.455 vs.2.900 ± 0.245,3.890 ± 0.367 vs.1.750 ± 0.256,1.790 ± 0.224 vs.0.590 ± 0.054）（P ＜ 0.01）.There was significant difference in the average number of transferred tiny lymph node N1,N2,N3 between experimental group and control group （1.090 ±0.087 vs.0.430 ± 0.044,0.550 ± 0.052 vs.0.340 ± 0.027,0.410 ± 0.044 vs.0.130 ± 0.013）（P ＜ 0.05）.There was no significant difference in postoperative complications,mortality and length of hospital stay（P＞ 0.05）.Conclusion Carbon nanoparticle in gastrectomy of stomach neoplasms is a simple,safe,easy method,and it has certain supplementary role in conventional gastrectomy of stomach neoplasms.