2型糖尿病合并泌尿系感染的危险因素及病原体分析

Analysis of Risk Factors of Type 2 Diabetes Mellitus Complicated with Urinary Tract Infection and Pathogen

目的:探讨2型糖尿病合并泌尿系感染的危险因素及常见病原体。方法:观察176例经临床确诊的2型糖尿病合并泌尿系感染的患者与同期176例2型糖尿病非泌尿系感染的患者的病程、有无并发其他并发症及比较两组空腹血糖浓度、24 h尿蛋白、BUN、Cr的结果,并对2型糖尿病合并泌尿系感染检出的病原体进行回顾性分析。结果:176例2型糖尿病合并泌尿系感染的危险因素包括病程长、有并发症、血糖浓度高、尿蛋白、BUN、Cr高等多种因素有关,检出的病原体主要是大肠埃希菌61.9%,其次是表皮葡萄球菌10.8%,检出的肺炎克雷伯菌8.0%、白色假丝酵母菌5.7%、变形杆菌5.1%、鲍曼不动杆菌2.8%、阴沟肠杆菌2.3%、金黄色葡萄球菌1.7%、铜绿假单胞菌2.3%、粪链球菌2.3%、比例不高,但也不容忽视。结论:掌握2型糖尿病合并泌尿系感染的危险因素及明确病原体感染的类型可为临床提供及时、合理治疗的依据,更有效地防治2型糖尿病患者并发尿路感染,提高生存率及生活质量。

Objective：To investigate the risk factors of type 2 diabetes mellitus complicated with urinary tract infection and pathogen.Method：The patients were observed and 176 cases of patients with type 2 diabetes mellitus complicated with urinary tract infection in 176 cases of clinically diagnosed type 2 diabetic non urinary tract infection patients,with or without concurrent other complications,and compared between the two groups of fasting blood glucose,24 hours urine protein,BUN,Cr results,and the type 2 diabetes combined with urinary infection pathogens were retrospectively analyzed.Result：The risk of type 2 diabetes mellitus complicated with urinary tract infection factors including 176 cases of long duration,complications,blood glucose concentration was high. The urine protein,BUN,Cr,and other factors,the detection of pathogens were Escherichia coli（61.9%）,followed by Staphylococcus epidermidis（10.8%）, checked out Klebsiella pneumonia（8.0%）,Candida albicans（5.7%）,Proteus（5.1%）,Bauman Acinetobacter（2.8%）,Enterobacter cloacae（2.3%）,Staphylococcus aureus（1.7%）,Pseudomonas aeruginosa（2.3%）,Streptococcus faecalis（2.3%）,the ratio was not high,but also can not be ignored.Conclusion：Understanding the risk factors of type 2 diabetes mellitus complicated with urinary tract infection and type specific pathogens can provide reasonable basis for the clinical early treatment,prevention is more effective in patients with type 2 diabetes mellitus urinary tract infection,improve the survival rate and the quality of life.