补肾健脾方治疗放射工作者亚健康疲劳的临床研究

Therapeutic Effect of Bushen Jianpi Recipe for Sub-health Fatigue of Medical Workers Exposing to Radioactive Rays

【目的】调查放射工作者亚健康疲劳的发生率,观察补肾健脾方治疗放射工作者亚健康疲劳的临床疗效。【方法】以广州市各级医疗卫生机构1 056名放射工作者为调查对象,采用流行病学调查和随机对照临床试验方法,从中抽取符合纳入标准的60例,随机分为治疗组和对照组各30例,对照组给予健康宣教、促进健康生活方式干预,治疗组在此基础上给予自拟补肾健脾方治疗,疗程4周,观察2组干预前后《多维疲劳量表》与《疲劳症状观察表》积分情况并评价疗效。【结果】(1)有效回收问卷976份,有效回收率为92.4%。976名放射工作者中,亚健康者652人(66.8%),亚健康疲劳者205人,占亚健康状态人群31.4%。(2)临床试验表明,治疗组总有效率为80.0%,对照组为36.7%,治疗组的临床总疗效优于对照组,2组比较差异有统计学意义(P<0.01)。(3)治疗后,治疗组的疲劳量表得分和疲劳症状积分均显著下降(P<0.01),而对照组治疗后均有所下降,其中疲劳症状积分的下降差异有统计学意义(P<0.05);治疗组疲劳量表得分和疲劳症状积分的下降作用均优于对照组(P<0.05或P<0.01)。【结论】放射工作者亚健康疲劳的发生率较高,补肾健脾方可以有效缓解这一状态。

Objective To investigate the incidence of sub-health fatigue among medical workers exposing to radioactive rays, and to observe the therapeutic effect of Bushen Jianpi recipe on sub-health fatigue. Methods An investigation was carried out among 1 056 medical workers exposing to radioactive rays which were from the medical and sanitary institutions of Guangzhou city. Sixty cases subjecting to the inclusion criteria were sampled from the investigated population by epidemiological methods for the randomized controlled trial. The subjects were evenly randomized into treatment group and control group. Both groups received health education and health-promoting lifestyle, and the treatment group was given self-prescribed Bushen Jianpi recipe additionally. The treatment lasted for 4 weeks. The scores of Multidimensional Fatigue Inventory （MFI-20） and Sub-health Measurement Scale Version 1.0 （SHMS V1.0） were observed before and after treatment, and the therapeutic effect was evaluated after treatment. Results （1） We got 976 effective questionnaires, and the effective response rate was 92.4%. Among the admitted 976 workers, the incidence of sub-heahh state was 66.8% （652/ 976） and that of sub-health fatigue is 31.4% （205/976）. （2） The total effective rate was 80.0% in the treatment group and was 36.7% in the control group, the difference being significant （P〈0.01）. （3） After treatment, the scores of MFI-20 and SHMS V1.0 were decreased in the treatmeat group, and fatigue symptom scores were decreased in the control group （P〈0.05 or P〈0.01）, the decrease in the treatment group being superior to that in the control group （P〈0.05 or P〈0.01）. Conclusion The incidence of sub-health fatigue is popular in the medical workers exposing to radioactive rays, and Bushen Jianpi recipe has an effect on improving the sub-health fatigue.