盐酸羟考酮注射液复合芬太尼及丙泊酚应用于无痛人工流产术的效果

Effect of oxycodone hydrochloride injection combined with fentanyl and propofol on painless induced abortion

目的探讨盐酸羟考酮注射液复合芬太尼及丙泊酚用于无痛人工流产术(简称人流术)的临床效果。方法选取自愿施行无痛人流术的孕妇100例,随机分为两组,观察组用盐酸羟考酮注射液+芬太尼+丙泊酚麻醉,对照组用芬太尼+丙泊酚麻醉,观察两组孕妇的心率、平均动脉压、血氧饱和度、宫口松弛情况、术毕意识恢复情况、术后宫缩痛、不良反应等状况。结果两组孕妇意识消失、意识恢复时间、术中出血量以及血液动力学的变化比较差异无统计学意义(P>0.05);两组孕妇宫口松弛度及术后不良反应发生率比较,观察组优于对照组(P<0.05)。结论盐酸羟考酮注射液复合芬太尼及丙泊酚用于无痛人流术是一种较理想的麻醉方法。

Objective To investigate the effect of oxycodone hydrochloride injection combined with fentanyl and propofol on painless induced abortion. Methods 100 early pregnancy women underwent painless induced abortion were randomly divided into two groups：observation group using oxycodone hydrochloride injection combined with fentanyl and propofol for intravenous anesthesia, and control group receiving fentanyl and propnfol. The heart rate （HR）, mean artery pressure （ MAP ） , pulse oxygen saturation （ SpO~ ） , cervix chalasis degree, pain of uterus contraction of post - operation, side effect of two groups were recorded. Results The consciousness extinction time and recovery time, blood loss during operation, MAP, HR and SpO2 had no statistical difference between two groups （P 〉 0. 05 ）. The statistical difference in the cervix chalasis degree and the incidence of side effect between two groups were found（P 〈 0. 05）. Conclusion Oxycodone hydrochloride injection combined with fentanyl and propofol is an ideal method for aesthesia in painless induced abortion.