连续性血液净化在老年危重症患者急性肾损伤中的临床应用

The Clinical Effect of Continuous Blood Purification Treatment in Elderly Critically Acute Kidney Injury Patients

目的:探讨对老年危重症急性肾损伤患者进行连续性血液净化的治疗效果。方法:将2012年1月-2014年1月的140例于本院ICU监护病房住院治疗的老年危重症急性肾损伤患者作为研究对象,按照随机双盲对照分配的原则分为观察组和对照组,其中对照组患者主要给予常规的老年危重症急性肾损伤治疗措施,而观察组患者在对照组治疗措施的基础上辅以连续性的血液净化治疗,观察两组患者的治疗效果及各项化验结果的变化。结果:观察组患者治疗后的系统评分和对照组相比显著降低,差异具有统计学意义(P<0.05);观察组患者各项指标(动脉血气pH值、尿素氮、HCO3-、血肌酐、电解质)均优于对照组(P<0.05)。结论:对老年危重症急性肾损伤患者在常规治疗的基础上辅以连续性的血液净化治疗,不仅可以显著提高患者的临床治愈率,而且能够显著改善机体内环境的紊乱,值得推广。

Objective： To explore the clinical effect of continuous blood purification treated in elderly critically acute kidney injury patients.Method： 140 elderly critically acute kidney injury patients were selected form ICU in our hospital during January 2012 and January 2014, who were divided into observation group and control group by randomly and double-blind principles. The control group was treated by conventional elderly critically acute kidney injury treatment, and observation group was adopted continuous blood purification beside the conventional elderly critically acute kidney injury treatment. We compared the treatment effects and test results between the two groups.Result：The observation group was better than the control group in system test scores after treatment, and the difference was significantly（P〈0.05）. In various indicators （such as arterial blood gas pH, blood urea nitrogen, HCO3-, serum creatinine, electrolytes）, the observation group was better than the control group, and the difference was significant（P〈0.05）. Conclusion： Continuous blood purification beside the conventional elderly critically acute kidney injury treatment can improve the clinical cure rate and the disorder of body internal environment, so it is worth to promote in clinical.