细辛脑注射液对毛细支气管炎患儿血清中多种指标的影响研究

Influence of asarone injection on serum disease factors and immune indexes of children with bronchiolitis

目的研究及观察细辛脑注射液对毛细支气管炎患儿血清疾病因子及免疫指标的影响。方法选取本院诊治的76例毛细支气管炎患儿为研究对象,将76例患儿遵循随机分配的方式分为对照组(常规毛细支气管炎治疗组)38例和观察组(常规治疗加细辛脑注射液组)38例,然后将两组患儿治疗前与治疗后第3天、第5天时的血清疾病相关因子及体液、细胞免疫指标进行对比。结果观察组治疗后第3天和第5天时的血清LTE4、IL-4及ECP均低于对照组治疗后,而血清IFN-γ则高于对照组,且体液和细胞免疫指标均分别显著好于对照组治疗后,P均<0.05,两组患儿治疗后的检测指标间均有显著性差异。结论细辛脑注射液可显著改善毛细支气管炎患儿的血清疾病因子及免疫指标水平。

Objective To study and observe the influence of asarone injection on serum disease factors and immune indexes of children with bronchiolitis. Methods 76 children with bronchiolitis were randomly and evenly divided into the control group and the observation group. All patients were given routine bronchiolitis treatment,and the observation group was additionally given asarone injection. Then the serum disease factors and humor,cellular immune indexes were observed at the third and fifth days after the treatment. Results The serum LTE4,IL-4 and ECP of the observation group at the third and fifth days after the treatment were all lower than those of the control group,while the serum IFN-γ was higher than that in the control group. The humor and cellular immune indexes were all significantly better in the observation group than in the control group after the treatment（ P〈0. 05）. Conclusion The influence of asarone injection can significantly improve the serum disease factors and immune indexes of children with bronchiolitis,so it＇s worthy of widely clinical application.