蒙药肋柱花氯仿提取物的化学成分研究

Mongolian Lomatogonium rotatum(L.)Fries ex Nym chemical constituents of the the chloroform extract

目的:研究肋柱花[Lomatogonium rotatum(L.)Fries exNym]氯仿提取物的化学成分。方法:利用硅胶柱色谱、Seph-adex LH-20柱色谱和HPLC等方法进行分离纯化,根据理化性质及光谱数据确定化合物的结构。结果:分离得到4个化合物,分别鉴定为1erythrocentaurin;21-羟基-3,7,8-三甲氧基口山酮;38-羟基-1,3,5-三甲基口山酮;41-羟基-3,5,8-三甲氧基口山酮。

Objective：Research Lomatogonium rotatum （L.）Fries ex Nym chemical composition of the chloroform extract. Methods： Silica gel column chromatography, Seph-adex LH-20 column chromatography and HPLC separation and purification methods, determine the structure of the compounds according to the physicochemical properties and spectral data. Re-sults： Result： From the chloroform extraction 4 compounds were isolated, identified as ①erythrocentaurin; ②1-hydroxy-3,7,8-trimethoxyxanthone; ③8-dihydroxy-1,3,5-trimethoxyxanthone;④1-dihydroxy-3,5,8-trimethoxyxanthone.