大籽獐牙菜抗氧化作用的实验研究

Experimental study on the antioxidant effect of Swertia Macrosperma

目的:研究大籽獐牙菜的抗氧化作用。方法:通过测定大籽獐牙菜不同提取部位的总抗氧化能力和对肝脏自发性脂质过氧化作用,获得总抗氧化能力较强的提取部位以及抗脂质过氧化作用较强的提取部位,同时考察这两个提取部位不同浓度对总抗氧化能力以及抗脂质过氧化作用的影响。进一步考察酮类化合物对兔肝脏自发性脂质过氧化的影响,同时考察不同浓度酮类化合物的影响。结果:大籽獐牙菜的乙酸乙酯提取部位具有较强的总抗氧化能力和脂质抗氧化作用,并呈现量效关系;酮类化合物具有抗脂质过氧化作用,并呈现量效关系。结论:大籽獐牙菜具有很强的提高血浆总抗氧化能力及抗肝脏自发性脂质过氧化的作用。

Objective： To study the antioxidant effect of Swertia Macrosperma. Methods： Determinate the T-AOC and lipid peroxidation in liver of different Swertia Maerosperma extracts to obtain the stronger extracts. We also investigate the lipid peroxidation in liver of different xanthones to obtain the stronger xanthone. Results：The ethyl acetate extract of Swertia Maerosperma present the stronger T-AOC and lipid peroxidation resistance with concentration relationship; The xanthone also present the lipid peroxidation resistance with concentration relationship. Conclusion： Swertia Macrosperma has strong T-AOC and lipid peroxidation resistance and the xanthone has strong lipid peroxidation resistance.