针灸治疗冠心病临床选穴规律的数据挖掘研究

The Principles of Acupoint Selection in Treatment of Coronary Artery Disease Based on Data Mining

目的研究针灸治疗冠状动脉粥样硬化性心脏病(冠心病)临床选穴规律。方法从CNKI、万方、维普、PubMed数据库收集1991-2013年针灸治疗冠心病的临床文献,建立冠心病选穴数据库,对数据进行统计描述、关联规则分析和聚类分析。结果 1991-2013年每年论文发表的数量无显著性差异,使用频率最高的腧穴依次为内关、心俞、膻中;相关性最高的腧穴是内关-心俞;临床选穴符合冠心病的病因病机特点;根据聚类分析结果,这些腧穴可分为重点穴和选配穴两大类。结论针灸治疗冠心病有规律可循,根据文献分析所发现的组方规律与该病的病机、病证相符,为针灸治疗冠心病的临床选穴提供了参考。

OBJECTIVE To excavate the principles of acupoint selection for coronary artery disease （CAD） by using statis tics and data mining methods.METHODS The literatures meeting the inclusive criteria on CAD were collected from three major Chinese database and PubMed database from 1991 to 2013.With these literatures,we collected data of acupoints for CAD treatment and then did descriptive analysis,association analysis and clustering analysis to the data.RESULTS There was no significant difference in the number of papers published in 1991-2013.Neiguan （PC6）,Xinshu （BL15）,and Danzhong （RN17） were listed as the top three acupionts with the highest frequency of application.The correlation analysis showed that Neiguan （PC6） and Xinshu （BL15） had the highest correlativity.The clustering analysis figured out the key acupoints group and optional acupoints group.CONCLUSION The study discussed the principles of acupoint selection in the treatment of CAD,at least partly suggesting the principles for clinical application of acupuncture and moxibustion treatment on coronary artery diseases.