2006—2012年山西省脊髓灰质炎减毒活疫苗免疫效果分析

Effects of oral polio vaccine in Shanxi province from 2006 to 2012

目的评价山西省脊髓灰质炎减毒活疫苗(OPV)免疫接种率及效果。方法通过OPV常规免疫报告接种率、估算接种率、调查接种率、补充免疫接种率、历年人群OPV抗体水平检测结果,对全省的OPV免疫接种情况和效果进行评价。结果山西省2006—2012年<12月龄OPV第3剂次(OPV3)报告接种率为99.72%,48月龄OPV报告接种率为99.58%;以当年乙型肝炎疫苗首针和含麻类疫苗实种人数估算OPV接种率分别为97.24%和101.22%;调查接种率为98.21%;补充免疫接种率一轮和二轮分别为98.39%和98.49%;健康人群脊灰抗体阳性率Ⅰ、Ⅱ、Ⅲ型分别为96.69%、96.10%、96.69%。结论山西省OPV接种率和健康人群中脊灰抗体阳性率较高。

Objective To assess the immunization coverage and effects of oral polio vaccine （OPV） in Shanxi Province.Methods OPV immunological effect was evaluated by the reported immunization coverage,estimated immunization coverage,surveyed immunization coverage,reported supplementary immunization coverage of OPV and the poliomyelitis antibody level in healthy population from 2006 to 2012.Results The reported immunization coverage of OPV was 99.72 % in children aged 12 months less than and 99.58 % in children aged 48 months from 2006 to 2012.Based on the actual number of the first dose of hepatitis B vaccine and measles vaccine,the estimated immunization coverage of OPV was 99.24% and 101.22%.The surveyed immunization coverage was 98.21% from 2006 to 2012.The supplementary immunization coverage of OPV was 98.39% and 98.49% in the first and second round.The positive rates of the poliomyelitis antibodyⅠ,Ⅱ and Ⅲ were 96.69%,96.10% and 96.69% in healthy population,respectively.Conclusion The OPV immunization coverage and positive rates of poliomyelitis antibody are high in healthy people in Shanxi province.