成年男性身体脂肪含量与肺通气功能及代谢指标的关系

Relationship between percentage body fat and lung ventilation function and metabolic index in adult males

目的：研究成年男性身体脂肪含量及分布与肺通气功能及代谢指标的关系。方法抽取来我院行健康体检男性600人，年龄22～77岁，进行调查问卷填写、人体成分分析、肺功能测定及血生化指标检测。分析体脂百分比（ percentage of body fat， PBF）、腰臀比（waist to hip ratio， WHR）与肺活量（vital capacity， VC）、用力呼气肺活量（force vital capacity，FVC）等肺通气功能指标的关系。结果20～45岁组PBF肥胖率、WHR肥胖率分别为70．68％、70．30％，低于45岁以上组（76．05％、81．74％），差异有统计学意义（P＜0．01）；PBF、WHR肥胖组与正常组相比，肺通气功能均明显下降；PBF与VC、FVC、FEV1、PEF呈负相关，与FEV1/FVC 呈正相关；WHR与VC、FVC、FEV1、PEF呈负相关。 WHR 与FPG、UA、TG、LDL-C呈正相关。结论成年男性PBF升高和中心性肥胖是肺通气功能下降损伤和代谢紊乱的危险因素。

Objective To investigate the effect of the body fat content and distribution on pulmonary ventilatory function and related metabolic index in the adult males .Methods Based on cluster sampling , we enrolled 600 healthy adult males aged 22-77 years in this hospital from November 2012 to April 2014.The basic data were obtained through the questionnaire survey .Finally we ex-amined the relationship between the percentage body fat （PBF）, waist-hip ratio（WHR） and VC,FVC,FEVl,FEV1/VC,FEV1/FVC, PEF,FPG,UA,TG,TC,HDL-C, LDL-C.Results WHR tended to increase along with age .PBF obesity rate and WHR obesity rate tended to increase with age .Compared with the normal group , the pulmonary ventilation function reduced significantly in PBF and WHR obesity group.There was a negative correlation between PBF and VC , FVC, FEV, PEF.But PBF showed an obvious positive correlation with FEV1 /FVC.PBF was positively associated with FPG , UA, TG, TC, HDL-C and LDL-C.WHR was positively corre-lated with FPG、UA、TG and LDL-C.Conclusions Increase in PBF and central obesity in adult males are the risk factors of pulmonary ventilation function impairment and metabolic disorders .