花蕊石、煅花蕊石重金属及砷盐含量限度标准制定

Standard Establishment of Contents of Deposit Heavy Metals and Arsenic Salts in Ophicalcitum and Calcined Ophicalcitum

目的:制定花蕊石和煅花蕊石中重金属及砷盐等有害元素的含量限度,有效控制该药的质量。方法:采用比色法和古蔡氏法分别测定花蕊石和煅花蕊石中重金属、砷盐含量。结果:测得不同产地的10批样品花蕊石和煅花蕊石含重金属少于2μg·g-1,含砷量少于0.5μg·g-1。结论:该测定方法简便、快速、准确,能有效控制花蕊石和煅花蕊石的质量。

Objective：Establish the check method of deposit heavy metals and arsenic salts in ophicalcitum and calcined ophicalcitum. Methods：Deposit heavy metals and arsenic salts in ophicalcitum and calcined ophicalcitum were detected by colorimetric method and Gu-Cai method. Results：The content determination of deposit heavy metals in 10 batches of ophicalcitum and calcined ophicalcitum from different origins was less than 2 μg·g-1. The content determination of arsenic salts was less than 0.5 μg·g-1. Conclusion：The method is simple,accurate and can be used to control the quality of ophicalcitum and calcined ophicalcitum.