103例肺部感染合并糖尿病的预后危险因素及预防措施探讨

Prognosis Risk Factors and Preventive Measures of Pulmonary Infection Combined with Diabetes in 103 Cases

目的 探讨导致糖尿病患者出现肺内感染的危险影响因素,并总结其预防措施。方法 选择2012年8月至2013年8月贵州省人民医院治疗的103例肺部感染合并糖尿病患者及同期住院接受治疗的136例糖尿病未合并肺部感染患者,对患者临床资料进行分析,观察影响感染发生的因素。结果 两组间血糖控制不佳、高胆固醇血症、β2微球蛋白异常及D-二聚体异常患者比较差异有统计学意义（P〈0.05）,同时血糖控制不佳（OR 2.348,95%CI 1.117~4.896）、高胆固醇血症（OR1.823,95%CI 1.115~4.896）、β2微球蛋白异常（OR 1.702,95%CI 1.023~5.987）及D-二聚体异常（OR 1.685,95%CI 1.022~5.232）为影响肺部感染合并糖尿病的危险因素（P〈0.05）。结论 临床要积极控制患者血糖、血脂及微球蛋白及D-二聚体水平,以减少糖尿病患者合并肺部感染的发生。

Objective To study the risk factors of lung infection in patients with diabetes and the prevention measures. Methods A total of 103 cases of diabetic patients with pulmonary infection from Guizhou Province People＇s Hospital during Aug. 2012 and Aug. 2013 were included as observation group, and 136 cases of diabetes mellitus without pulmonary infection from the same hospital during the same period were included as control group. The patients＇ clinical data were retrospectively analyzed, and the influencing factors of infection were observed. Results Poor glycemic control, hypercholesterolemia, [32 mieroglobulin abnormalities and patients with abnormal D-direct of the two groups had statistically significant differences （ P 〈 0.05 ）, and poor glycemic control （ OR ： 2. 348 ; 95% CI： 1.117-4. 896 ） , hypercholesterolemia （ OR ： 1. 823 ; 95 % CI： 1. 115-4. 896 ）, 132 -mieroglobulin abnormalities （ OR ： 1. 702 ; 95 % CI： 1. 023-5. 987 ） and D-dimer abnormalities （OR： 1. 685;95% CI： 1. 022-5. 232） were risk factors for the affected lung infection combined with diabetes （P 〈 0.05 ）. Conclusion Active control of blood sugar blood lipids and microglobulin and D-direct levels should be done in clinical to reduce the incidence of lung infections combined ~th diabetes.