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肺结核患者外周血CD8^+ CD122^+ T细胞亚群及血清白细胞介素-10含量分析 被引量:5

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摘要 目的检测肺结核患者外周血CD8+CD122+T细胞亚群及血清白细胞介素-10(IL-10)含量,并分析其临床意义。方法收集40例肺结核患者和20例健康志愿者通过流式细胞术检测外周血CD8+CD122+T细胞亚群,ELISA检测血清IL-10含量。结果肺结核患者外周血CD8+CD122+T细胞亚群及血清IL-10含量明显高于健康志愿者,差异有统计学意义(P<0.05)。痰涂Mtb阳性患者外周血CD8+CD122+T细胞亚群及血清IL-10含量显著高于痰涂Mtb阴性患者,差异有统计学意义(P<0.05)。肺结核患者外周血CD8+CD122+T细胞亚群与血清IL-10含量呈正相关(P<0.05)。结论 CD8+CD122+T细胞可能在肺结核发生发展中起着重要作用。
出处 《广东医学》 CAS CSCD 北大核心 2014年第18期2858-2860,共3页 Guangdong Medical Journal
基金 广东省医学科研基金立项项目(编号:B2013427) 广东省东莞市医疗卫生科技计划(编号:20131051010139)
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参考文献9

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二级参考文献19

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