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新生儿血小板减少症294例临床分析 被引量:11

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摘要 目的分析新生儿血小板减少症的病程特点、病因、转归等临床特点。方法分析294例新生儿血小板减少症患儿的临床资料。结果新生儿血小板减少症发病率7.2%。294例血小板减少症新生儿中,早产儿213例(72.4%),低体重儿201例(68.4%),比足月儿和正常体重儿更容易发生血小板减少症(P<0.000 1)。早期血小板减少症95例(32.3%),晚期199例(67.7%)。轻度血小板减少症144例(49.1%),重度血小板减少症150例(50.9%)。早期病例的最常见原因为免疫性(26.3%)、感染(18.9%)、母亲先兆子痫或妊娠期高血压疾病(17.9%)和宫内发育迟缓(13.7%)。83.4%的晚期病例的病因是感染。新生儿血小板减少症139例(47.3%)合并出血事件,其中合并重症出血事件34例(11.6%),病死率5.4%。结论新生儿血小板减少症发病率较高,早产儿、低体重儿是发病危险人群。早期病例的常见病因是胎盘功能不良,晚期病例的最常见原因是感染。新生儿血小板减少症易合并出血事件,病死率高,应予以重视。
出处 《广东医学》 CAS CSCD 北大核心 2014年第18期2865-2867,共3页 Guangdong Medical Journal
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