期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

老年高血压患者血浆同型半胱氨酸浓度与动脉壁僵硬度的相关性研究 被引量：1

Correlation between serum homocysteine level and arterial stiffness in elderly patients with hypertension
下载PDF
导出
摘要 目的探讨老年高血压患者动脉脉搏波速率与血管危险因子同型半胱氨酸浓度的关系。方法选取2012年2月—2013年2月在本院老年科住院的老年高血压患者52例,在空腹状态下测定血浆同型半胱氨酸浓度及动脉脉搏波速率。结果血浆同型半胱氨酸浓度与脉搏波速率具有显著相关性(r=0.8854,P<0.001)。结论在血压控制的情况下,老年高血压患者血浆同型半胱氨酸浓度与脉搏波速率呈正相关。 Objective To explore correlation between pulse wave velocity （PWV）and serum homocysteine （Hcy）level in elderly patients with hypertension.Methods 52 elderly patients with hypertension were collected and the PWV and Hcy level were detected on an empty stomach.The measures of total plasma homocysteine and of PWV were taken on the same day.Results There was a significant correlation between PWV and Hcy level （t=13.47,P〈0.001 ）.Conclusion When the blood pressure is well controlled,there is a positive relationship between PWV and Hcy level.
作者 邵炀
机构地区 南京医科大学附属无锡第二人民医院老年科
出处 《实用临床医药杂志》 CAS 2014年第17期15-17,共3页 Journal of Clinical Medicine in Practice
关键词 同型半胱氨酸 脉搏波速率 老年型高血压 动脉硬化 homocysteine pulse wave velocity geriatric hypertension arterial stiffness
分类号 R544.1 [医药卫生—心血管疾病]
  • 相关文献

参考文献25

  • 1Ashis Mookerjee, AhmedM. A1-Jumaily, Andrew Low. Arte- rial pulse wave velocity measurement: different techniques, similar results-implications for medical devices[J]. Biomech Model Mechanobiol, 2010, 9: 773.
  • 2Oliver J J, Webb D J. Noninvasive assessment of arterial stiff- ness and risk of atherosclerotic events [ J ]. Arterioscler Thromb Vasc Biol, 2003, 23 : 554.
  • 3Mujumdar V S, Aru G M, and Tyagi S C. Induction of oxida- tive stress by homocysteine impairs endothelial function[J]. J Cell Biochem, 2001, 82: 491.
  • 4Heinecke J S. Superoxide mediated oxidation of low-density lipoproteins by thiols[ M]. New York: Lissm 1988 : 433.
  • 5Selwyn A P. Prothrombotic and antithrombotic pathways in a- cute coronary syndromes[ J]. Am J Cardiol, 2003, 91 : 3.
  • 6Hart S R, Mangoni A A, Swift C G, et al. Effect of methio- nine loading on pulse wave analysis in elderly volunteers[ J]. Postgrad Med J, 2006, 82 : 524.
  • 7Steed M M, Tyagi S C. Mechanisms of cardiovascular remode- ling in Hyperhomocysteinemia[ J]. Antioxidants & Redox Sig- naling Vol, 2011, 15: 1927.
  • 8Ventura E, Durant R, Jaussent A, et al. Homocysteine and inflammation as main determinants of oxidative stress in the elderly[J]. Free Radic Biol Med, 2009, 46(6) : 737.
  • 9Vyssoulis G, Karpanou E, Kyvelou S-M, et al. Associations between plasma homocysteine levels, aortic stiffness and wave reflection in patients with arterial hypertension, isolated office hypertension and normotensive controls [ J ]. J Human Hyper- tension,2010, 24: 183.
  • 10Steppan J, Barodka V, Berkowitz D. E, et al. Vascular Stiff- ness and Increased Pulse Pressure in the Aging Cardiovascular System[ J]. Cardiology Research and Practice, 2011: 8.

二级参考文献29

  • 1杨宁,林洪丽,李龙凯,赵光本,周娜,张瑜,姜雪.血液透析患者桡动脉增强指数与腹主动脉钙化指数、颈动脉内膜厚度的影响因素分析[J].中国血液净化,2012,11(9):493-496. 被引量：1
  • 2中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量：5223
  • 3Anand SS, Yusuf S, Vuksan V, et al. Differences in risk factors, atheroselerosis and cardiovascular disease between ethnic groups in Canada: the study of health assessment and risk in ethnic groups (SHARE) [J]. Indian Heart J, 2000, 52(7 Suppl): S35-43.
  • 4Sacco RL, Adams R, Albers G, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for health care professionals from the American heart association/American stroke association council on stroke: co-sponsored by the council on cardiovascular radiology and intervention: the American academy of neurology affirms the value of this guideline[J]. Stroke, 2006, 37(2): 577-617.
  • 5Crouse JR, Harpold GH, Kahl FR, et al. Evaluation of a scoring system for extracranial carotid atherosclerosis extent with B-mode ultrasound[J]. Stroke, 1986, 17(2): 270-5.
  • 6Eiskjaer H, Christensen T, Pedersen B. Increased stiffness and crossectional area of femoral artery in essential hypertension recorded by ultrasotmd[M]. Raren press, 1989: 129-33.
  • 7Mendis S, Athauda SB, Naser M, et al. Association between hyperhomocysteinaemia and hypertension in Sri Lankans [J]. J Int Med Res, 1999, 27(1): 38-44.
  • 8Lim U, Cassano PA. Homocysteine and blood pressure in the third national health and nutrition examination survey[J]. Am J Epidemiol, 2002, 156(12): 1105-13.
  • 9Krupinski J, Font A, Luque A, et al. Angiogenesis and inflammation in carotid atherosclerosis[J]. Front Biosci, 2008, 13(1): 6472-82.
  • 10Amar J, Ruidavets JB, Peyrieux JC, et al. C-reactive protein elevation predicts pulse pressure reduction in hypertensive subjects [J]. Hypertension, 2005, 46(1): 151-5.

共引文献93

同被引文献9

引证文献1

二级引证文献7

实用临床医药杂志
2014年 第17期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部