Q-开关Nd:YAG 1064nm激光联合谷胱甘肽凝胶治疗黄褐斑的疗效观察

Effective observation of Q-switch Nd:YAG 1064nm laser combined with glutathione gel for the treatment of melasma

目的：评估Q-开关Nd∶YAG 1 064nm激光联合谷胱甘肽凝胶对黄褐斑的治疗效果.方法：选26例黄褐斑患者,随机分为两组.治疗组1 3例,接受Q-开关Nd：YAG激光联合谷胱甘肽凝胶治疗;对照组13例,仅采用Q-开关Nd∶ YAG激光治疗,每14天治疗1次,6～10次为1个疗程,疗程结束后判断疗效.结果：治疗组有效率为100％,对照组为84.6％,两组疗效比较有统计学意义（P＜0.05）.结论：临床对比观察Q-开关Nd∶YAG 1 064nm激光联合谷胱甘肽凝胶治疗黄褐斑较单用Q-开关Nd∶YAG 1 064nm激光治疗有明显优势,适合推广应用.

Objective To evaluate Q-switch Nd∶YAG 1064nm laser combined with Glutathione gel the therapeutic effect for the treatment of Melasma.Methods 26 patients with melasma divided into the treatment group and the control group.13 cases were treated by Q-switched Nd∶YAG 1064nm laser and glutathione gel for treatment group and 13 cases were only treated by Q-switched Nd∶ YAG 1064nm.The patients were treated by every two weeks,6～10 times as a course.The curative effect was judged after the end of a course.Results effective rate of 100% in treatment group and 84.6% in control group.The two groups had statistical significance （P〈0.05）.Conclusion The clinical observation have more advantage using Q-switched Nd∶ YAG 1064nm laser and Glutathione gel than single using laser for treatment of melasma.lt is suitable for clinical application.