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儿童闭塞性细支气管炎23例临床研究 被引量:3

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摘要 目的 探讨儿童闭塞性细支气管炎(BO)的临床特点及疗效.方法 对本院确诊的23例BO患儿的临床表现、辅助检查及诊治预后资料进行回顾性分析.结果 23例BO患儿反复咳嗽、喘息>6周,肺部有喘鸣音及湿罗音.病因:21例(91.4%)感染后诱发BO,1例(4.3%)重症渗出性多形性红斑(SJS)后诱发BO,1例(4.3%)溶血尿毒综合征后诱发BO.23例肺CT示存在气体潴留征象,典型马赛克灌注征者12例,磨玻璃影者8例,合并肺实变者5例,有支气管扩张者5例,肺间质表现1例.16例肺功能检查,其中14例示阻塞性通气功能障碍,2例混合性通气功能障碍.10例纤维支气管镜检查均示支气管内膜炎症,3例合并喉-气管软化.患儿采用扩张支气管(沙丁胺醇2.5 ~5 mg/次,布地奈德0.5~1 mg/次)剂雾化吸入及口服激素和阿奇霉素治疗,7例因病情加重反复住院多次.结论 儿童BO多由感染引起,以慢性咳嗽及喘息、胸部CT马赛克灌注征、肺功能阻塞性通气功能障碍为临床特征.干预患儿感染性疾病,以激素联合阿奇霉素治疗,可缓解症状,但远期疗效不佳.
出处 《中国医师杂志》 CAS 2014年第8期1126-1128,共3页 Journal of Chinese Physician
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参考文献12

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