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白假丝酵母菌生物膜群体感应分子与EFG1研究进展 被引量:1

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摘要 白假丝酵母菌属于念珠菌属,为人类最常见的致病菌,感染后可引起皮肤黏膜念珠菌病、内脏念珠菌病及念珠菌血症等.近20年,由于广谱抗生素、糖皮质激素及免疫抑制剂的普遍应用,器官及骨髓的大量移植,导管介入治疗的大力推广,真菌感染中白假丝酵母菌病的发病率逐年增加.Sifu-entes-Osornio等[1]进行了流行病学调查显示,美国各大医院白假丝酵母菌的感染率为0.82‰~0.96‰,欧洲为0.2‰ ~0.38‰,拉丁美洲为1.2‰~5.5‰.在我国,白假丝酵母菌血症的发病率为0.71‰~0.85‰[2],重症监护室患者白假丝酵母菌的感染率为9.6‰,病死率波动在20%~63%[3].
作者 李晴 冯文莉
出处 《中国医师杂志》 CAS 2014年第8期1143-1145,共3页 Journal of Chinese Physician
基金 山西省基础研究项目(2012011045-3) 山西省青年科技研究基金(2012011035-3) 山西医科大学科技创新基金(01201013)
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