软肝降脂胶囊治疗稳定性心绞痛的临床疗效

Clinical efficacy of Ruanganjiangzhi capsule in treating stable angina

目的探讨软肝降脂胶囊改善稳定性心绞痛疗效。方法稳定性心绞痛患者45例,随机均分为三组,分别予口服辛伐他汀、软肝降脂胶囊辛伐他汀加软肝降脂胶囊,30d后观察治疗前后患者临床症状和血脂、C-反应蛋白(CRP)等指标的变化。结果三组总体疗效相仿;治疗后,临床症状均有改善,血清甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL-C)和CRP指标降低,高密度脂蛋白(HDL-C)增加。软肝降脂胶囊组肝功能有改善。结论软肝降脂胶囊可以调节稳定性心绞痛患者血脂以及CRP水平,延缓动脉粥样硬化进程。

Objective To observe the clinical efficacy of Ruanganjiangzhi capsule in treating stable angina. Methods Forty-five patients with stable angina were equally randomized into three groups of A（treated with oral simvastatin）, B（treated with oral Ruanganjiangzhi capsule） and C （treated with oral simvastatin and Ruanganjiangzhi capsule）. The changes in clinical symptoms and serum levels of lipids, C reactive protein（CRP） and liver functions before and after 30 days of therapy were compared among three groups. Results The overall efficacy of three groups was similar. Compared to before treatment, the clinical symptoms were improved, serum levels of triglyceride, cholesterol, low density lipoprotein cholesterol and CRP were decreased, and serum high-density lipoprotein cholesterol was increased after 30 days therapy in three groups. There were no significant changes in liver functions in group C after treatment. Conclusion Ruanganjiangzhi capsule may regulate blood lipids and CRP, which is beneficial to delaying the process of atherosclerosis in the patients with stable angina.