2011~2013年安阳市疑似预防接种异常反应监测

Surveillance an Suspected Adverse Events Following Immunization,Anyang City,2011-2013

目的分析安阳市疑似预防接种异常反应（AEFI）的发生特征,评价AEFI监测系统运转状况。方法通过AEFI监测系统,收集全市2011~2013年报告的AEFI个案数据,采用描述性方法,对相关指标进行流行病学分析。结果 2011~2013年AEFI监测系统共收到个案363例,其中≤1岁占55.56%,男女性别比为1.66∶1,报告疫苗以全国计划免疫（NIP）疫苗为主;一般反应占88.43%,其中78.24%发生在接种后≤1d;异常反应占9.92%,以过敏性皮疹和卡介苗淋巴结炎为主。估算全市NIP疫苗疑似预防接种异常反应报告发生率为4.54/10万。结论全市AEFI系统的监测质量逐年提高。AEFI常发生在小年龄组儿童接种NIP疫苗时,应为监测重点;NIP疫苗不良反应报告发生率均在预期发生范围内。

Objective To analyze the occurrence characteristics of Adverse Event Following Immunization （AEFI） in An- yang city,so as to evaluate the implementation of AEFI surveillance system. Methods Data were collected on AEFI case reported from 2011 to 2013 through the AEFI Information System, to analyze relevant indicators using descriptive epidemiology. Results The AEFI monitoring system received a total of 363 cases from 2011 to 2013,among them, targets aged ≤1 year accounted for 55.56% ,the sex ratio of male and female was 1.66 ： 1. NIP vaccine had high incidence of AE- FIs. 88.43% AEFIs were common, among them 78.24 % occurred ≤ 1 after vaccination;abnormal reaction rate of 9.92%, Allergic rash and BCG lymphadenitis mainly. The vaccine reaction estimated reporting rate of NIP vaccines was 4.54/102. Conclusion The quality of AEFI surveillance is raised year by year. AEFIs often occur in young children and NIP vaccines,and they are the focus of the AEFI surveillance. The reported reaction rates of NIP vaccines occur in the expected range.