中医分期治疗视网膜静脉阻塞的临床研究

Clinical observation on treating retinal vein occlusion in TCM

目的:观察中医分期治疗视网膜静脉阻塞(RVO)的临床疗效。方法:将70例(70眼)RVO患者随机分为试验组(n=35)和对照组(n=35)。对照组予肠溶阿司匹林等抗凝治疗,有新生血管形成或黄斑区水肿者采用激光封闭治疗,试验组同时联合中药分早、中、晚期治疗,行视力测量,裂隙灯显微镜检查,检眼镜查眼底,荧光素眼底血管造影(FFA)。结果:①试验组视力改善、不变和恶化分别为14眼(40.00%)、19眼(54.29%)和2眼(5.71%),对照组分别是5眼(14.29%)、27眼(77.14%)和3眼(8.57%),Z=-2.239,P=0.025。②试验组眼底出血吸收,眼底血管渗漏减少优于对照组。③试验组痊愈、好转和无效分别是10眼(28.57%)、23眼(65.71%)和2眼(5.71%),对照组分别是5眼(14.29%)、21眼(60.00%)和9眼(25.71%),Z=-2.324,P=0.020。结论:中医分期治疗联合西医常规干预RVO的效果优于单纯西医治疗。

Objective： To observe clinical effects of TCM on RVO. Methods： 70 cases were randomly divided into the experimental group and the control group, 35 cases for each. The control group was given anticoagulant therapy （enteric-coated aspirin） and laser closed treatment; while the control group was given TCM treatment, and visual acuity, slit lamp microscopy, fundus and FFA were checked. Results： I. In the experimental group, 14 eyes （40.00%） were improved, 19 eyes （54.29%） were unchanged and 2 eyes （5.71%） were deteriorate, while in the control group 5 eyes （14.29%） were improved, 27 eyes （77.14%） were unchanged and 3 eyes （8.57%） were deteriorate. II. Retinal hemorrhage absorption and reduction of retinal vascular leakage in the experimental group was better than that in the control group. III. In the experimental group, 10 eyes were cured （28.57%）, 23 eyes （65.71%） were improved and 2 eyes （5.71%） were invalid, while 5 eyes （14.29%） were cured, 21 eyes （60.00%） were improved and 9 eyes （25.71%） were invalid. Conclusion： The efficacy of the integrative medicine on treating RVO was better than western medicine treatment.