格列奈类促泌剂的临床认识

The clinical experience of glinides

格列奈类促泌剂是国内常用的非磺脲类胰岛素促泌剂,主要包括瑞格列奈和那格列奈。文章将从其在国内外的应用、降糖效果、不良反应、与胰岛素的合用、在CKD中的使用以及用药原则等方面阐述对格列奈类药物的临床认识。

Glinides are nonsulfonylurea insulin secretagogues which are commonly used in China, mainly including repaglinide and nateglinide. In the article, the clinical experience of glinides will be stated including its application at home and abroad, hypoglycemic effect, adverse effect, the combination with insulin, the application in the patients with CKD, the medication principle, and so on.