杨硕平教授加减防己黄芪汤治疗小儿肾病综合征(风水相搏型)46例临床观察

Professor Yang Shuo-ping plus-minus against oneself Huang Qi Tang intreatment of nephrotic syndrome(Feng Shui-combination) clinical observation of 46 cases

目的：观察加减防己黄芪汤对小儿肾病综合征的治疗效果.方法：将46例肾病综合征小儿患者随机分为观察组和对照组,观察组在对照组治疗的基础上辨证给予加减防己黄芪汤;对照组给予强的松1.5～2mg/（kg？d）治疗,控制饮食、严格控制食盐的摄入和相关对症处理.观察两组治疗前后相关指标的变化.结果：治疗6个月后观察组24h尿蛋白定量、低蛋白血症及血浆胆固醇与对照组比较,有显著性差异（P〈0.05）.结论：加减防己黄芪汤治疗小儿肾病综合征在缓解水肿,降低尿蛋白及纠正低蛋白血症和缓解其他临床症状效果明显.

Objective： To observe the curative effect of alter-integrated Fangji Huangqi Decoction in the treatment of infantilenephrotic syndrome. Method： 46 cases with infantile nephrotic syndrome were randomly divide into the observation group and the controlgroup. Patients in the observation group were given alter-integrated Fangji Huangqi Decoction based on syndrome differentiation exceptthe therapy for the control group; patients in the control group were treated with prednisone 1.5-2mg/（kg ？ d） the diet, salt in taking andrelated symptoms were strictly controlled. The changes of correlated indexes of the two groups were observed. Results： The 24h urineprotein quota, the low proteinemia and the blood plasma cholesterol of the observation group were compared with those of the controlgroup after 6 months with significant difference （P〈0.05）. Conclusion： Alter-integrated Fangji Huangqi Decoction has a significant effecton reliving edema, reducing the urine protein, treating the low proteinemia and other clinical symptoms of infantile nephrotic syndrome.